Prediction of intravenous immunoglobulin resistance in Kawasaki disease in an East China population

The objectives of the study were to find the risk factors associated with intravenous immunoglobulin (IVIG) resistance and generate a prediction scoring system of IVIG resistance in patients with Kawasaki disease (KD). We retrospectively reviewed the clinical records of KD patients between January 2...

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Bibliographic Details
Published in:Clinical rheumatology 2016-11, Vol.35 (11), p.2771-2776
Main Authors: Tang, Yunjia, Yan, Wenhua, Sun, Ling, Huang, Jie, Qian, Weiguo, Ding, Yueyue, Lv, Haitao
Format: Article
Language:English
Subjects:
C-Reactive Protein - analysis
Child
Child, Preschool
China
Drug Resistance
Female
Humans
Immunoglobulins, Intravenous - therapeutic use
Infant
Male
Medicine
Medicine & Public Health
Mucocutaneous Lymph Node Syndrome - drug therapy
Original Article
Retrospective Studies
Rheumatology
Risk Factors
Sensitivity and Specificity
Serum Albumin - analysis
Treatment Failure
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Summary:The objectives of the study were to find the risk factors associated with intravenous immunoglobulin (IVIG) resistance and generate a prediction scoring system of IVIG resistance in patients with Kawasaki disease (KD). We retrospectively reviewed the clinical records of KD patients between January 2006 and December 2014. Multivariate logistic regression was performed to identify the risk factors of IVIG non-responders. The independent risk factors were used to construct a new scoring system and compared with Kobayashi and Egami scoring systems. Multivariate logistic regression analysis identified age
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-016-3370-2