A Simple and Facile Glucose Biosensor Based on Prussian Blue Modified Graphite String

This work describes the string sensor for the simple and sensitive detection of glucose which is based on Prussian blue (PB) modified graphite utilizing dipping. First, PB modified graphite (PB-G) strings are characterized by physical and electrochemical techniques to optimize the PB-G layer thickne...

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Bibliographic Details
Published in:Journal of sensors 2016-01, Vol.2016 (2016), p.1-6
Main Authors: Lee, Gi-Ja, Park, Hun-Kuk, Chung, Joo-Ho, Lee, Seung Ho
Format: Article
Language:English
Subjects:
Analgesics
Aqueous solutions
Chitosan
Electrodes
Enzymes
Glucose
Graphite
Lead (metal)
Potassium
Screen printing
Sensors
Strings
Studies
Thickness
Uric acid
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Summary:This work describes the string sensor for the simple and sensitive detection of glucose which is based on Prussian blue (PB) modified graphite utilizing dipping. First, PB modified graphite (PB-G) strings are characterized by physical and electrochemical techniques to optimize the PB-G layer thickness. Then, glucose oxidase (GOx) is immobilized on PB-G string electrode with biocompatible chitosan overlayer (Chi/GOx/PB-G). The Chi/GOx/PB-G string electrode exhibits a sensitivity of 641.3 μA·mM−1·cm−2 to glucose with a linear range of 0.03 to 1.0 mM ( R 2 = 0.9957 ) and a rapid response time (
ISSN:1687-725X
1687-7268
DOI:10.1155/2016/1859292