Levels of High-Density Lipoprotein Cholesterol are Associated With Biomarkers of Inflammation in Patients With Acute Coronary Syndrome

Pathologic conditions associated with inflammation show an inverse correlation between high-density lipoprotein cholesterol (HDL-C) and inflammatory biomarker levels. Our aim was to investigate, in patients with acute coronary syndrome (ACS), whether very low HDL-C levels are associated with inflamm...

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Bibliographic Details
Published in:The American journal of cardiology 2015-12, Vol.116 (11), p.1651-1657
Main Authors: González-Pacheco, Héctor, MD, Amezcua-Guerra, Luis M., MD, Vazquez-Rangel, Armando, MD, MSc, Martínez-Sánchez, Carlos, MD, Pérez-Méndez, Oscar, PhD, Verdejo, Juan, MD, Bojalil, Rafael, MD, PhD
Format: Article
Language:English
Subjects:
Acute Coronary Syndrome - blood
Acute Coronary Syndrome - mortality
Acute coronary syndromes
Acute-Phase Reaction - blood
Aged
Albumin
Biomarkers
Biomarkers - blood
C-reactive protein
C-Reactive Protein - analysis
Cardiology
Cardiovascular
Cholesterol
Cholesterol, HDL - blood
Cross-Sectional Studies
Female
Heart attacks
High density
High density lipoprotein
Hospital Mortality
Humans
Inflammation
Inflammation - blood
Leukocyte Count
Leukocytes
Male
Middle Aged
Mortality
Multivariate Analysis
Serum albumin
Serum Albumin - analysis
Serum levels
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Description
Summary:Pathologic conditions associated with inflammation show an inverse correlation between high-density lipoprotein cholesterol (HDL-C) and inflammatory biomarker levels. Our aim was to investigate, in patients with acute coronary syndrome (ACS), whether very low HDL-C levels are associated with inflammatory biomarkers. In a cross-sectional study, we included 6,134 patients with ACS; they were classified as having very low (
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2015.09.009