Bronchoalveolar Lavage Fluid from Pneumocystis carinii-Infected Rats Inhibits Phagocytosis in Normal Alveolar Macrophages

Alveolar macrophages from Pneumocystis carinii (P. carinii)-infected rats are defective in phagocytosis. To investigate whether this defect is due to certain factors present in the lung during active P. carinii infection, alveolar macrophages from normal rats were incubated with bronchoalveolar lava...

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Bibliographic Details
Published in:The Journal of eukaryotic microbiology 2001-06, Vol.48 (s1), p.163s-164s
Main Authors: LASBURY, M. E., DURANT, P. J., LEE, C. H.
Format: Article
Language:English
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Summary:Alveolar macrophages from Pneumocystis carinii (P. carinii)-infected rats are defective in phagocytosis. To investigate whether this defect is due to certain factors present in the lung during active P. carinii infection, alveolar macrophages from normal rats were incubated with bronchoalveolar lavage (BAL) fluids from P. carinii-infected rats. BAL fluid from normal rats challenged with P. carinii was added to alveolar macrophages from P. carinii-infected rats to see if they could correct the phagocytic defect.
ISSN:1066-5234
1550-7408
DOI:10.1111/j.1550-7408.2001.tb00502.x