Clinical features of soft tissue sarcoma presenting intra-tumour haematoma: case series and review of the literature

• Published in: International orthopaedics 2017, Vol.41 (1), p.203-209
• Main Authors: Hoshi, Manabu, Oebisu, Naoto, Ieguchi, Makoto, Ban, Yoshitaka, Takami, Masatsugu, Nakamura, Hiroaki
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Female; Hematoma - etiology; Humans; Magnetic Resonance Imaging; Male; Medicine; Medicine & Public Health; Middle Aged; Neoplasm Recurrence, Local; Original Paper; Orthopedics; Retrospective Studies; Sarcoma - complications; Sarcoma - diagnosis; Sarcoma - therapy; Survival Rate
• ISSN: 0341-2695; 1432-5195
• DOI: 10.1007/s00264-016-3322-0

Introduction Intra-tumour haematoma is an uncommon clinical presentation in malignant soft tissue tumours. This study aimed to highlight the clinical features of patients with soft tissue sarcomas with intra-tumour haematoma. Methods The patient group was composed of eight men and one woman aged between 29 and 83 years (mean 44.0 ± 20.8). The average follow-up was 29.8 months. Clinical information, including clinical features, radiological information and treatment course, was retrospectively investigated. Results Tumours were predominantly located in the chest wall and thigh, and average diameter was 10.3 cm. Six patients underwent needle biopsy with ultrasound sonography, and three underwent an open biopsy. Histological diagnoses indicated that all tumours were high grade, three of which were undifferentiated pleomorphic sarcomas, three synovial sarcomas, two pleomorphic liposarcomas, one a leiomyosarcoma and one a malignant peripheral nerve sheath tumour. The median diagnostic delay time was 3.0 months. Magnetic resonance imaging (MRI) indicated a haematoma area