Selection for high and low oxygen consumption‐induced differences in maintenance energy requirements of mice

• Published in: Animal science journal 2017-07, Vol.88 (7), p.959-965
• Main Authors: Darhan, Hongyu, Kikusato, Motoi, Toyomizu, Masaaki, Roh, Sang‐gun, Katoh, Kazuo, Sato, Masahiro, Suzuki, Keiichi
• Format: Article
• Language: English
• Subjects: Age; Animal behavior; Animals; Body Size; Conversion ratio; Deposition; Eating - physiology; Energy consumption; Energy intake; Energy Intake - physiology; Energy Metabolism; Energy requirements; Feed conversion; Feed efficiency; Lipid Metabolism; Maintenance; maintenance energy requirement; Metabolism; Mice; Mice, Inbred Strains; Oxygen consumption; Oxygen Consumption - physiology; Physical growth; Proteins - metabolism; selection
• ISSN: 1344-3941; 1740-0929
• DOI: 10.1111/asj.12740

Maintenance energy requirements (MER) of mice selected for high (H) or low (L) oxygen consumption (OC) were compared. Forty‐four mice from H and L OC lines were weaned at 3 weeks and divided into four experimental groups: group A were sacrificed at 4 weeks; group B were fed ad libitum, and groups C and D were fed 2.8 and 2.4 g/day, respectively, from 4 to 8 weeks of age. Groups B–D were sacrificed at 8 weeks. Chemical components were estimated for all groups. MER was estimated using a model that partitioned metabolizable energy intake into that used for maintenance, and protein and fat deposition. The feed conversion ratio for the B group was significantly higher in the H than in the L line. Feed intake for metabolic energy content per metabolic body size was significantly also higher in the H line, whereas accumulated energy content per metabolic body size was significantly higher in the L line. MER of the H line was greater than that of the L line (P