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In vitro anticancer activity of silver nanoparticle synthesized by Escherichia coli VM1 isolated from marine sediments of Ennore southeast coast of India
•The observed lattice fringes display indicates that the nanoparticles were good crystals.•This is conceivably the first report on the anticancer activity of Ag NPs synthesized by marine E. coli VM1.•The observed results indubitably supports that Ag NPs synthesized by marine E. coli give new hope as...
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| Published in: | Enzyme and microbial technology 2016-12, Vol.95, p.146-154 |
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| Main Authors: | , , |
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| cited_by | cdi_FETCH-LOGICAL-c408t-2b9320c9d06ff047519d48d819dbb9bd6eef89a4b13f5c9f9dfce1b68fc39c633 |
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| cites | cdi_FETCH-LOGICAL-c408t-2b9320c9d06ff047519d48d819dbb9bd6eef89a4b13f5c9f9dfce1b68fc39c633 |
| container_end_page | 154 |
| container_issue | |
| container_start_page | 146 |
| container_title | Enzyme and microbial technology |
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| creator | Maharani, Viswanathan Sundaramanickam, Arumugam Balasubramanian, Thangavel |
| description | •The observed lattice fringes display indicates that the nanoparticles were good crystals.•This is conceivably the first report on the anticancer activity of Ag NPs synthesized by marine E. coli VM1.•The observed results indubitably supports that Ag NPs synthesized by marine E. coli give new hope as anticancer agents.
In the present investigation, the bacterium Escherichia coli (VM1) was isolated from a marine sediments of Ennore coastal water along southeast coast of India was exploited for its capability of Ag NPs synthesis. The derived nanoparticles were characterized employing ultraviolet–visible (UV–vis) spectroscopy, Fourier Transform Infrared (FTIR) spectroscopy, X-ray diffraction and High Resolution Transmission Electron Microscopy (HRTEM) studies. The Ag NPs were further subjected to MTT assay to evaluate their anticancer activity against human lung cancer cell line (A549), human cervical cancer cell line (HeLa) and normal (Vero) cell line. The marine E. coli (VM1) synthesized silver nanoparticles exhibited considerable cytotoxic influence against human cancer cell lines, thereby suggesting that they have tremendous potential as effective anticancer agents. |
| doi_str_mv | 10.1016/j.enzmictec.2016.09.008 |
| format | article |
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In the present investigation, the bacterium Escherichia coli (VM1) was isolated from a marine sediments of Ennore coastal water along southeast coast of India was exploited for its capability of Ag NPs synthesis. The derived nanoparticles were characterized employing ultraviolet–visible (UV–vis) spectroscopy, Fourier Transform Infrared (FTIR) spectroscopy, X-ray diffraction and High Resolution Transmission Electron Microscopy (HRTEM) studies. The Ag NPs were further subjected to MTT assay to evaluate their anticancer activity against human lung cancer cell line (A549), human cervical cancer cell line (HeLa) and normal (Vero) cell line. The marine E. coli (VM1) synthesized silver nanoparticles exhibited considerable cytotoxic influence against human cancer cell lines, thereby suggesting that they have tremendous potential as effective anticancer agents.</description><identifier>ISSN: 0141-0229</identifier><identifier>EISSN: 1879-0909</identifier><identifier>DOI: 10.1016/j.enzmictec.2016.09.008</identifier><identifier>PMID: 27866610</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>A549 Cells ; Animals ; Anticancer activity ; Antineoplastic Agents - chemistry ; Antineoplastic Agents - pharmacology ; Biosynthesis ; Cercopithecus aethiops ; Drug Screening Assays, Antitumor ; Escherichia coli ; Escherichia coli - classification ; Escherichia coli - isolation & purification ; Escherichia coli - metabolism ; Geologic Sediments - microbiology ; Green Chemistry Technology ; HeLa Cells ; Humans ; In Vitro Techniques ; India ; Metal Nanoparticles - chemistry ; Metal Nanoparticles - ultrastructure ; Silver - chemistry ; Silver - pharmacology ; Silver nanoparticle ; Spectroscopy, Fourier Transform Infrared ; Vero Cells</subject><ispartof>Enzyme and microbial technology, 2016-12, Vol.95, p.146-154</ispartof><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-2b9320c9d06ff047519d48d819dbb9bd6eef89a4b13f5c9f9dfce1b68fc39c633</citedby><cites>FETCH-LOGICAL-c408t-2b9320c9d06ff047519d48d819dbb9bd6eef89a4b13f5c9f9dfce1b68fc39c633</cites><orcidid>0000-0002-2682-445X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27866610$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Maharani, Viswanathan</creatorcontrib><creatorcontrib>Sundaramanickam, Arumugam</creatorcontrib><creatorcontrib>Balasubramanian, Thangavel</creatorcontrib><title>In vitro anticancer activity of silver nanoparticle synthesized by Escherichia coli VM1 isolated from marine sediments of Ennore southeast coast of India</title><title>Enzyme and microbial technology</title><addtitle>Enzyme Microb Technol</addtitle><description>•The observed lattice fringes display indicates that the nanoparticles were good crystals.•This is conceivably the first report on the anticancer activity of Ag NPs synthesized by marine E. coli VM1.•The observed results indubitably supports that Ag NPs synthesized by marine E. coli give new hope as anticancer agents.
In the present investigation, the bacterium Escherichia coli (VM1) was isolated from a marine sediments of Ennore coastal water along southeast coast of India was exploited for its capability of Ag NPs synthesis. The derived nanoparticles were characterized employing ultraviolet–visible (UV–vis) spectroscopy, Fourier Transform Infrared (FTIR) spectroscopy, X-ray diffraction and High Resolution Transmission Electron Microscopy (HRTEM) studies. The Ag NPs were further subjected to MTT assay to evaluate their anticancer activity against human lung cancer cell line (A549), human cervical cancer cell line (HeLa) and normal (Vero) cell line. The marine E. coli (VM1) synthesized silver nanoparticles exhibited considerable cytotoxic influence against human cancer cell lines, thereby suggesting that they have tremendous potential as effective anticancer agents.</description><subject>A549 Cells</subject><subject>Animals</subject><subject>Anticancer activity</subject><subject>Antineoplastic Agents - chemistry</subject><subject>Antineoplastic Agents - pharmacology</subject><subject>Biosynthesis</subject><subject>Cercopithecus aethiops</subject><subject>Drug Screening Assays, Antitumor</subject><subject>Escherichia coli</subject><subject>Escherichia coli - classification</subject><subject>Escherichia coli - isolation & purification</subject><subject>Escherichia coli - metabolism</subject><subject>Geologic Sediments - microbiology</subject><subject>Green Chemistry Technology</subject><subject>HeLa Cells</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>India</subject><subject>Metal Nanoparticles - chemistry</subject><subject>Metal Nanoparticles - ultrastructure</subject><subject>Silver - chemistry</subject><subject>Silver - pharmacology</subject><subject>Silver nanoparticle</subject><subject>Spectroscopy, Fourier Transform Infrared</subject><subject>Vero Cells</subject><issn>0141-0229</issn><issn>1879-0909</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqFkUFvEzEQhS0EoqHlL4CPXHYZ724262NVBYhU1Evp1fLaY2WiXTvYTqT0n_BvcZTSKxeP9PzeG40-xj4LqAWI_uuuRv88k8lo6qYINcgaYHjDFmJYyQokyLdsAaITFTSNvGIfUtoBFKGD9-yqWQ193wtYsD8bz4-UY-DaZzLaG4xcm0xFPPHgeKLpWCSvfdjrWCwT8nTyeYuJntHy8cTXyWwxktmS5iZMxJ9-Ck4pTDoXg4th5rOO5EsQLc3oczo3r70PsWjhUMp0yiV7fsvPxlvSN-yd01PCjy_zmv36tn68-1HdP3zf3N3eV6aDIVfNKNsGjLTQOwfdaimk7QY7lDGOcrQ9ohuk7kbRuqWRTlpnUIz94EwrTd-21-zLpXcfw-8DpqxmSganSXsMh6TE0DXLrhdLUayri9XEkFJEp_aRymknJUCduaideuWizlwUSFW4lOSnlyWHcUb7mvsHohhuLwYspx4Jo0qGsNCwFNFkZQP9d8lfA3GnYA</recordid><startdate>20161201</startdate><enddate>20161201</enddate><creator>Maharani, Viswanathan</creator><creator>Sundaramanickam, Arumugam</creator><creator>Balasubramanian, Thangavel</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2682-445X</orcidid></search><sort><creationdate>20161201</creationdate><title>In vitro anticancer activity of silver nanoparticle synthesized by Escherichia coli VM1 isolated from marine sediments of Ennore southeast coast of India</title><author>Maharani, Viswanathan ; Sundaramanickam, Arumugam ; Balasubramanian, Thangavel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-2b9320c9d06ff047519d48d819dbb9bd6eef89a4b13f5c9f9dfce1b68fc39c633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>A549 Cells</topic><topic>Animals</topic><topic>Anticancer activity</topic><topic>Antineoplastic Agents - chemistry</topic><topic>Antineoplastic Agents - pharmacology</topic><topic>Biosynthesis</topic><topic>Cercopithecus aethiops</topic><topic>Drug Screening Assays, Antitumor</topic><topic>Escherichia coli</topic><topic>Escherichia coli - classification</topic><topic>Escherichia coli - isolation & purification</topic><topic>Escherichia coli - metabolism</topic><topic>Geologic Sediments - microbiology</topic><topic>Green Chemistry Technology</topic><topic>HeLa Cells</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>India</topic><topic>Metal Nanoparticles - chemistry</topic><topic>Metal Nanoparticles - ultrastructure</topic><topic>Silver - chemistry</topic><topic>Silver - pharmacology</topic><topic>Silver nanoparticle</topic><topic>Spectroscopy, Fourier Transform Infrared</topic><topic>Vero Cells</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maharani, Viswanathan</creatorcontrib><creatorcontrib>Sundaramanickam, Arumugam</creatorcontrib><creatorcontrib>Balasubramanian, Thangavel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Enzyme and microbial technology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Maharani, Viswanathan</au><au>Sundaramanickam, Arumugam</au><au>Balasubramanian, Thangavel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In vitro anticancer activity of silver nanoparticle synthesized by Escherichia coli VM1 isolated from marine sediments of Ennore southeast coast of India</atitle><jtitle>Enzyme and microbial technology</jtitle><addtitle>Enzyme Microb Technol</addtitle><date>2016-12-01</date><risdate>2016</risdate><volume>95</volume><spage>146</spage><epage>154</epage><pages>146-154</pages><issn>0141-0229</issn><eissn>1879-0909</eissn><abstract>•The observed lattice fringes display indicates that the nanoparticles were good crystals.•This is conceivably the first report on the anticancer activity of Ag NPs synthesized by marine E. coli VM1.•The observed results indubitably supports that Ag NPs synthesized by marine E. coli give new hope as anticancer agents.
In the present investigation, the bacterium Escherichia coli (VM1) was isolated from a marine sediments of Ennore coastal water along southeast coast of India was exploited for its capability of Ag NPs synthesis. The derived nanoparticles were characterized employing ultraviolet–visible (UV–vis) spectroscopy, Fourier Transform Infrared (FTIR) spectroscopy, X-ray diffraction and High Resolution Transmission Electron Microscopy (HRTEM) studies. The Ag NPs were further subjected to MTT assay to evaluate their anticancer activity against human lung cancer cell line (A549), human cervical cancer cell line (HeLa) and normal (Vero) cell line. The marine E. coli (VM1) synthesized silver nanoparticles exhibited considerable cytotoxic influence against human cancer cell lines, thereby suggesting that they have tremendous potential as effective anticancer agents.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27866610</pmid><doi>10.1016/j.enzmictec.2016.09.008</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-2682-445X</orcidid></addata></record> |
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| ispartof | Enzyme and microbial technology, 2016-12, Vol.95, p.146-154 |
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| language | eng |
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| source | ScienceDirect Freedom Collection |
| subjects | A549 Cells Animals Anticancer activity Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Biosynthesis Cercopithecus aethiops Drug Screening Assays, Antitumor Escherichia coli Escherichia coli - classification Escherichia coli - isolation & purification Escherichia coli - metabolism Geologic Sediments - microbiology Green Chemistry Technology HeLa Cells Humans In Vitro Techniques India Metal Nanoparticles - chemistry Metal Nanoparticles - ultrastructure Silver - chemistry Silver - pharmacology Silver nanoparticle Spectroscopy, Fourier Transform Infrared Vero Cells |
| title | In vitro anticancer activity of silver nanoparticle synthesized by Escherichia coli VM1 isolated from marine sediments of Ennore southeast coast of India |
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