Ratiometric and photoconvertible fluorescent protein-based voltage indicator prototypes

To expand the toolbox of fluorescent protein-based voltage indicators, we explored two distinct protein design strategies. Using these design strategies, we created three new voltage indicators: a red intensiometric voltage indicator (tdFlicR Δ110AR), a green/red ratiometric voltage indicator (tdFli...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (98), p.14153-14156
Main Authors: Abdelfattah, A S, Rancic, V, Rawal, B, Ballanyi, K, Campbell, R E
Format: Article
Language:English
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Summary:To expand the toolbox of fluorescent protein-based voltage indicators, we explored two distinct protein design strategies. Using these design strategies, we created three new voltage indicators: a red intensiometric voltage indicator (tdFlicR Δ110AR), a green/red ratiometric voltage indicator (tdFlicR-VK-ASAP), and a green to red photoconvertible voltage indicator (FlicGR1).
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc06810c