Loading…
Myocardial perfusion and left ventricular quantitative parameters obtained using gated myocardial SPECT: Comparison of three software packages
The aim of the present study was to compare Emory Cardiac Toolbox, Myovation, and Quantitative Gated SPECT software regarding the automatic measurements of perfusion and functional left ventricular (LV) quantitative parameters, summed stress score (SSS), perfusion defect score, LV ejection fraction...
Saved in:
| Published in: | Journal of nuclear cardiology 2018-06, Vol.25 (3), p.911-924 |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c424t-d39f19d9937df97d7613233721a0bf463fa646994f4f6cfc200bac020c6fbfd33 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c424t-d39f19d9937df97d7613233721a0bf463fa646994f4f6cfc200bac020c6fbfd33 |
| container_end_page | 924 |
| container_issue | 3 |
| container_start_page | 911 |
| container_title | Journal of nuclear cardiology |
| container_volume | 25 |
| creator | Alexiou, Sotiria Georgoulias, Panagiotis Angelidis, George Valotassiou, Varvara Tsougos, Ioannis Psimadas, Dimitrios Lakiotis, Velissarios Kaspiri, Agaristi Alexopoulos, Dimitrios Apostolopoulos, Dimitrios Vassilakos, Pavlos |
| description | The aim of the present study was to compare Emory Cardiac Toolbox, Myovation, and Quantitative Gated SPECT software regarding the automatic measurements of perfusion and functional left ventricular (LV) quantitative parameters, summed stress score (SSS), perfusion defect score, LV ejection fraction (LVEF), end-diastolic volume, and end-systolic volume (ESV).
99mTc-tetrofosmin gated SPECT studies were performed in 634 consecutive patients based on the one-day stress/rest protocol. Participants were divided into subgroups according to heart size (ESV cut-off value: 25 mL), perfusion (SSS >/≤3), and other patient/protocol-related factors. LVEF was categorized as normal (≥50%), mildly moderately impaired (35–49%), and severely abnormal (25 mL, and SSS >3 subgroups (intraclass correlation coefficients, ICCs 0.73–0.93). In SSS ≤3 subgroup, the correlation was excellent for LV functional parameters, but suboptimal for perfusion variables (ICCs 0.30–0.83). LVEF categorization revealed similar variability (discordance 18.1 and 11.1% for stress/rest LVEF values, respectively). Pair comparisons demonstrated considerable differences concerning all parameters for all patient subgroups. The statistical significance of our findings by ESV and SSS classifications was evaluated.
Despite the significant concordance between software packages, considerable differences in mean values of myocardial perfusion and LV functional parameters were demonstrated. |
| doi_str_mv | 10.1007/s12350-016-0730-x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1842598827</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1071358123022717</els_id><sourcerecordid>2043017754</sourcerecordid><originalsourceid>FETCH-LOGICAL-c424t-d39f19d9937df97d7613233721a0bf463fa646994f4f6cfc200bac020c6fbfd33</originalsourceid><addsrcrecordid>eNp9kU1vFSEUhidGY2v1B7gxJG7cjPIxA4Oumpv6kdRoYl0TBg5X6gzcAnNt_4S_WW6m2sRFV5yE53k54W2a5wS_JhiLN5lQ1uMWE95iwXB7_aA5Jj2jLe978rDOWJCW9QM5ap7kfIkxlkzKx80RFYNghIvj5vfnm2h0sl5PaAfJLdnHgHSwaAJX0B5CSd4sk07oatGh-KKL3wPa6aRnKJAyimPRPoBF1Q1btNWlzvNd7LevZ5uLt2gT5yr5XOOjQ-VHAkA5uvJLp0Oc-am3kJ82j5yeMjy7PU-a7-_PLjYf2_MvHz5tTs9b09GutJZJR6SVkgnrpLCCE0YZE5RoPLqOM6d5x6XsXOe4cYZiPGqDKTbcjc4ydtK8WnN3KV4tkIuafTYwTTpAXLIiQ0d7OQxUVPTlf-hlXFKo2ymKO4aJEH1XKbJSJsWcEzi1S37W6UYRrA5lqbUsVctSh7LUdXVe3CYv4wz2n_G3nQrQFcj1Kmwh3T19X-q7VYL6f3tfpWw8BAPWJzBF2ejvsf8AJ5u1wg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2043017754</pqid></control><display><type>article</type><title>Myocardial perfusion and left ventricular quantitative parameters obtained using gated myocardial SPECT: Comparison of three software packages</title><source>Springer Link</source><creator>Alexiou, Sotiria ; Georgoulias, Panagiotis ; Angelidis, George ; Valotassiou, Varvara ; Tsougos, Ioannis ; Psimadas, Dimitrios ; Lakiotis, Velissarios ; Kaspiri, Agaristi ; Alexopoulos, Dimitrios ; Apostolopoulos, Dimitrios ; Vassilakos, Pavlos</creator><creatorcontrib>Alexiou, Sotiria ; Georgoulias, Panagiotis ; Angelidis, George ; Valotassiou, Varvara ; Tsougos, Ioannis ; Psimadas, Dimitrios ; Lakiotis, Velissarios ; Kaspiri, Agaristi ; Alexopoulos, Dimitrios ; Apostolopoulos, Dimitrios ; Vassilakos, Pavlos</creatorcontrib><description>The aim of the present study was to compare Emory Cardiac Toolbox, Myovation, and Quantitative Gated SPECT software regarding the automatic measurements of perfusion and functional left ventricular (LV) quantitative parameters, summed stress score (SSS), perfusion defect score, LV ejection fraction (LVEF), end-diastolic volume, and end-systolic volume (ESV).
99mTc-tetrofosmin gated SPECT studies were performed in 634 consecutive patients based on the one-day stress/rest protocol. Participants were divided into subgroups according to heart size (ESV cut-off value: 25 mL), perfusion (SSS >/≤3), and other patient/protocol-related factors. LVEF was categorized as normal (≥50%), mildly moderately impaired (35–49%), and severely abnormal (<35%). The concordance between the packages was good to excellent, in overall population, ESV ≤25 mL, ESV >25 mL, and SSS >3 subgroups (intraclass correlation coefficients, ICCs 0.73–0.93). In SSS ≤3 subgroup, the correlation was excellent for LV functional parameters, but suboptimal for perfusion variables (ICCs 0.30–0.83). LVEF categorization revealed similar variability (discordance 18.1 and 11.1% for stress/rest LVEF values, respectively). Pair comparisons demonstrated considerable differences concerning all parameters for all patient subgroups. The statistical significance of our findings by ESV and SSS classifications was evaluated.
Despite the significant concordance between software packages, considerable differences in mean values of myocardial perfusion and LV functional parameters were demonstrated.</description><identifier>ISSN: 1071-3581</identifier><identifier>EISSN: 1532-6551</identifier><identifier>DOI: 10.1007/s12350-016-0730-x</identifier><identifier>PMID: 27873167</identifier><language>eng</language><publisher>New York: Elsevier Inc</publisher><subject>Aged ; Algorithms ; Cardiology ; ECTb ; Ejection fraction ; Exercise Test ; Female ; Gated Blood-Pool Imaging ; Gated SPECT ; Humans ; Imaging ; left ventricular ejection fraction ; left ventricular volumes ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Myovation ; Nuclear Medicine ; Original Article ; QGS ; Radiology ; Reproducibility of Results ; Sensitivity and Specificity ; Software ; Software packages ; Stroke Volume - physiology ; Technetium ; Tomography, Emission-Computed, Single-Photon ; Ventricular Dysfunction, Left - diagnostic imaging ; Ventricular Dysfunction, Left - physiopathology</subject><ispartof>Journal of nuclear cardiology, 2018-06, Vol.25 (3), p.911-924</ispartof><rights>2018 American Society of Nuclear Cardiology. Published by ELSEVIER INC. All rights reserved.</rights><rights>American Society of Nuclear Cardiology 2016</rights><rights>Journal of Nuclear Cardiology is a copyright of Springer, (2016). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c424t-d39f19d9937df97d7613233721a0bf463fa646994f4f6cfc200bac020c6fbfd33</citedby><cites>FETCH-LOGICAL-c424t-d39f19d9937df97d7613233721a0bf463fa646994f4f6cfc200bac020c6fbfd33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27873167$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alexiou, Sotiria</creatorcontrib><creatorcontrib>Georgoulias, Panagiotis</creatorcontrib><creatorcontrib>Angelidis, George</creatorcontrib><creatorcontrib>Valotassiou, Varvara</creatorcontrib><creatorcontrib>Tsougos, Ioannis</creatorcontrib><creatorcontrib>Psimadas, Dimitrios</creatorcontrib><creatorcontrib>Lakiotis, Velissarios</creatorcontrib><creatorcontrib>Kaspiri, Agaristi</creatorcontrib><creatorcontrib>Alexopoulos, Dimitrios</creatorcontrib><creatorcontrib>Apostolopoulos, Dimitrios</creatorcontrib><creatorcontrib>Vassilakos, Pavlos</creatorcontrib><title>Myocardial perfusion and left ventricular quantitative parameters obtained using gated myocardial SPECT: Comparison of three software packages</title><title>Journal of nuclear cardiology</title><addtitle>J. Nucl. Cardiol</addtitle><addtitle>J Nucl Cardiol</addtitle><description>The aim of the present study was to compare Emory Cardiac Toolbox, Myovation, and Quantitative Gated SPECT software regarding the automatic measurements of perfusion and functional left ventricular (LV) quantitative parameters, summed stress score (SSS), perfusion defect score, LV ejection fraction (LVEF), end-diastolic volume, and end-systolic volume (ESV).
99mTc-tetrofosmin gated SPECT studies were performed in 634 consecutive patients based on the one-day stress/rest protocol. Participants were divided into subgroups according to heart size (ESV cut-off value: 25 mL), perfusion (SSS >/≤3), and other patient/protocol-related factors. LVEF was categorized as normal (≥50%), mildly moderately impaired (35–49%), and severely abnormal (<35%). The concordance between the packages was good to excellent, in overall population, ESV ≤25 mL, ESV >25 mL, and SSS >3 subgroups (intraclass correlation coefficients, ICCs 0.73–0.93). In SSS ≤3 subgroup, the correlation was excellent for LV functional parameters, but suboptimal for perfusion variables (ICCs 0.30–0.83). LVEF categorization revealed similar variability (discordance 18.1 and 11.1% for stress/rest LVEF values, respectively). Pair comparisons demonstrated considerable differences concerning all parameters for all patient subgroups. The statistical significance of our findings by ESV and SSS classifications was evaluated.
Despite the significant concordance between software packages, considerable differences in mean values of myocardial perfusion and LV functional parameters were demonstrated.</description><subject>Aged</subject><subject>Algorithms</subject><subject>Cardiology</subject><subject>ECTb</subject><subject>Ejection fraction</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Gated Blood-Pool Imaging</subject><subject>Gated SPECT</subject><subject>Humans</subject><subject>Imaging</subject><subject>left ventricular ejection fraction</subject><subject>left ventricular volumes</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Myovation</subject><subject>Nuclear Medicine</subject><subject>Original Article</subject><subject>QGS</subject><subject>Radiology</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Software</subject><subject>Software packages</subject><subject>Stroke Volume - physiology</subject><subject>Technetium</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><subject>Ventricular Dysfunction, Left - diagnostic imaging</subject><subject>Ventricular Dysfunction, Left - physiopathology</subject><issn>1071-3581</issn><issn>1532-6551</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp9kU1vFSEUhidGY2v1B7gxJG7cjPIxA4Oumpv6kdRoYl0TBg5X6gzcAnNt_4S_WW6m2sRFV5yE53k54W2a5wS_JhiLN5lQ1uMWE95iwXB7_aA5Jj2jLe978rDOWJCW9QM5ap7kfIkxlkzKx80RFYNghIvj5vfnm2h0sl5PaAfJLdnHgHSwaAJX0B5CSd4sk07oatGh-KKL3wPa6aRnKJAyimPRPoBF1Q1btNWlzvNd7LevZ5uLt2gT5yr5XOOjQ-VHAkA5uvJLp0Oc-am3kJ82j5yeMjy7PU-a7-_PLjYf2_MvHz5tTs9b09GutJZJR6SVkgnrpLCCE0YZE5RoPLqOM6d5x6XsXOe4cYZiPGqDKTbcjc4ydtK8WnN3KV4tkIuafTYwTTpAXLIiQ0d7OQxUVPTlf-hlXFKo2ymKO4aJEH1XKbJSJsWcEzi1S37W6UYRrA5lqbUsVctSh7LUdXVe3CYv4wz2n_G3nQrQFcj1Kmwh3T19X-q7VYL6f3tfpWw8BAPWJzBF2ejvsf8AJ5u1wg</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Alexiou, Sotiria</creator><creator>Georgoulias, Panagiotis</creator><creator>Angelidis, George</creator><creator>Valotassiou, Varvara</creator><creator>Tsougos, Ioannis</creator><creator>Psimadas, Dimitrios</creator><creator>Lakiotis, Velissarios</creator><creator>Kaspiri, Agaristi</creator><creator>Alexopoulos, Dimitrios</creator><creator>Apostolopoulos, Dimitrios</creator><creator>Vassilakos, Pavlos</creator><general>Elsevier Inc</general><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20180601</creationdate><title>Myocardial perfusion and left ventricular quantitative parameters obtained using gated myocardial SPECT: Comparison of three software packages</title><author>Alexiou, Sotiria ; Georgoulias, Panagiotis ; Angelidis, George ; Valotassiou, Varvara ; Tsougos, Ioannis ; Psimadas, Dimitrios ; Lakiotis, Velissarios ; Kaspiri, Agaristi ; Alexopoulos, Dimitrios ; Apostolopoulos, Dimitrios ; Vassilakos, Pavlos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c424t-d39f19d9937df97d7613233721a0bf463fa646994f4f6cfc200bac020c6fbfd33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Aged</topic><topic>Algorithms</topic><topic>Cardiology</topic><topic>ECTb</topic><topic>Ejection fraction</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Gated Blood-Pool Imaging</topic><topic>Gated SPECT</topic><topic>Humans</topic><topic>Imaging</topic><topic>left ventricular ejection fraction</topic><topic>left ventricular volumes</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Myovation</topic><topic>Nuclear Medicine</topic><topic>Original Article</topic><topic>QGS</topic><topic>Radiology</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Software</topic><topic>Software packages</topic><topic>Stroke Volume - physiology</topic><topic>Technetium</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><topic>Ventricular Dysfunction, Left - diagnostic imaging</topic><topic>Ventricular Dysfunction, Left - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alexiou, Sotiria</creatorcontrib><creatorcontrib>Georgoulias, Panagiotis</creatorcontrib><creatorcontrib>Angelidis, George</creatorcontrib><creatorcontrib>Valotassiou, Varvara</creatorcontrib><creatorcontrib>Tsougos, Ioannis</creatorcontrib><creatorcontrib>Psimadas, Dimitrios</creatorcontrib><creatorcontrib>Lakiotis, Velissarios</creatorcontrib><creatorcontrib>Kaspiri, Agaristi</creatorcontrib><creatorcontrib>Alexopoulos, Dimitrios</creatorcontrib><creatorcontrib>Apostolopoulos, Dimitrios</creatorcontrib><creatorcontrib>Vassilakos, Pavlos</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing & Allied Health Database</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of nuclear cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alexiou, Sotiria</au><au>Georgoulias, Panagiotis</au><au>Angelidis, George</au><au>Valotassiou, Varvara</au><au>Tsougos, Ioannis</au><au>Psimadas, Dimitrios</au><au>Lakiotis, Velissarios</au><au>Kaspiri, Agaristi</au><au>Alexopoulos, Dimitrios</au><au>Apostolopoulos, Dimitrios</au><au>Vassilakos, Pavlos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Myocardial perfusion and left ventricular quantitative parameters obtained using gated myocardial SPECT: Comparison of three software packages</atitle><jtitle>Journal of nuclear cardiology</jtitle><stitle>J. Nucl. Cardiol</stitle><addtitle>J Nucl Cardiol</addtitle><date>2018-06-01</date><risdate>2018</risdate><volume>25</volume><issue>3</issue><spage>911</spage><epage>924</epage><pages>911-924</pages><issn>1071-3581</issn><eissn>1532-6551</eissn><abstract>The aim of the present study was to compare Emory Cardiac Toolbox, Myovation, and Quantitative Gated SPECT software regarding the automatic measurements of perfusion and functional left ventricular (LV) quantitative parameters, summed stress score (SSS), perfusion defect score, LV ejection fraction (LVEF), end-diastolic volume, and end-systolic volume (ESV).
99mTc-tetrofosmin gated SPECT studies were performed in 634 consecutive patients based on the one-day stress/rest protocol. Participants were divided into subgroups according to heart size (ESV cut-off value: 25 mL), perfusion (SSS >/≤3), and other patient/protocol-related factors. LVEF was categorized as normal (≥50%), mildly moderately impaired (35–49%), and severely abnormal (<35%). The concordance between the packages was good to excellent, in overall population, ESV ≤25 mL, ESV >25 mL, and SSS >3 subgroups (intraclass correlation coefficients, ICCs 0.73–0.93). In SSS ≤3 subgroup, the correlation was excellent for LV functional parameters, but suboptimal for perfusion variables (ICCs 0.30–0.83). LVEF categorization revealed similar variability (discordance 18.1 and 11.1% for stress/rest LVEF values, respectively). Pair comparisons demonstrated considerable differences concerning all parameters for all patient subgroups. The statistical significance of our findings by ESV and SSS classifications was evaluated.
Despite the significant concordance between software packages, considerable differences in mean values of myocardial perfusion and LV functional parameters were demonstrated.</abstract><cop>New York</cop><pub>Elsevier Inc</pub><pmid>27873167</pmid><doi>10.1007/s12350-016-0730-x</doi><tpages>14</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1071-3581 |
| ispartof | Journal of nuclear cardiology, 2018-06, Vol.25 (3), p.911-924 |
| issn | 1071-3581 1532-6551 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1842598827 |
| source | Springer Link |
| subjects | Aged Algorithms Cardiology ECTb Ejection fraction Exercise Test Female Gated Blood-Pool Imaging Gated SPECT Humans Imaging left ventricular ejection fraction left ventricular volumes Male Medicine Medicine & Public Health Middle Aged Myovation Nuclear Medicine Original Article QGS Radiology Reproducibility of Results Sensitivity and Specificity Software Software packages Stroke Volume - physiology Technetium Tomography, Emission-Computed, Single-Photon Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - physiopathology |
| title | Myocardial perfusion and left ventricular quantitative parameters obtained using gated myocardial SPECT: Comparison of three software packages |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T20%3A28%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Myocardial%20perfusion%20and%20left%20ventricular%20quantitative%20parameters%20obtained%20using%20gated%20myocardial%20SPECT:%20Comparison%20of%20three%20software%20packages&rft.jtitle=Journal%20of%20nuclear%20cardiology&rft.au=Alexiou,%20Sotiria&rft.date=2018-06-01&rft.volume=25&rft.issue=3&rft.spage=911&rft.epage=924&rft.pages=911-924&rft.issn=1071-3581&rft.eissn=1532-6551&rft_id=info:doi/10.1007/s12350-016-0730-x&rft_dat=%3Cproquest_cross%3E2043017754%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c424t-d39f19d9937df97d7613233721a0bf463fa646994f4f6cfc200bac020c6fbfd33%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2043017754&rft_id=info:pmid/27873167&rfr_iscdi=true |