Postoperative antibiotic use and the incidence of intra-abdominal abscess in the setting of suppurative appendicitis: a retrospective analysis

Although guidelines exist for postoperative antibiotic use in acute appendicitis that is perforated, gangrenous, or simple/uncomplicated, there are less data about its use in suppurative appendicitis. Here, we targeted this subgroup of patients to determine whether postoperative antibiotic administr...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of surgery 2016-12, Vol.212 (6), p.1121-1125
Main Authors: Bae, Esther, Dehal, Ahmed, Franz, Vanessa, Joannides, Michael, Sakis, Nicholas, Scurlock, Joshua, Nguyen, Patrick, Hussain, Farabi
Format: Article
Language:English
Subjects:
Abdomen
Abdominal Abscess - epidemiology
Acute Disease
Adult
Anti-Bacterial Agents - therapeutic use
Antibiotic stewardship
Antibiotics
Appendectomy
Appendicitis
Appendicitis - pathology
Appendicitis - surgery
Body mass index
Complications
Diabetes
Female
Heart rate
Hospitals
Humans
Hypertension
Incidence
Infection
Infections
Intra-abdominal abscess
Laparoscopy
Male
Patients
Postoperative Care
Retrospective Studies
Suppuration
Suppurative appendicitis
Surgery
Surgical Wound Infection - epidemiology
Tobacco
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Although guidelines exist for postoperative antibiotic use in acute appendicitis that is perforated, gangrenous, or simple/uncomplicated, there are less data about its use in suppurative appendicitis. Here, we targeted this subgroup of patients to determine whether postoperative antibiotic administration affects incidence of intra-abdominal abscess formation. We retrospectively examined 1,192 patients who underwent laparoscopic appendectomy for acute appendicitis at Kaiser Permanente Fontana Hospital between August 2010 and August 2013. Suppurative appendicitis was described for 143 (12%) patients. Fifty-two patients received postoperative antibiotics for at least 1 week on discharge home, 91 did not. Of 143 patients with suppurative appendicitis, 1 (1.9%) who received postoperative antibiotics came back with an intra-abdominal abscess within 1 month. Of the 91 patients in the no antibiotic group, 1 (1.1%) came back with an intra-abdominal abscess. The administration of postoperative antibiotic in the setting of suppurative appendicitis has no effect on the rate of intra-abdominal abscess formation. Routine postoperative antibiotics may not be necessary in this patient population, and more evidence is needed to justify its use.
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2016.09.010