Automated detection of bone metastatic changes using serial CT scans

Highlights • Sclerotic and lytic bone metastases are quantified in spine, ribs, and sternum. • The volumes registered by weighted-Demons and symmetric warping are subtracted. • Many metastases missed by radiologists are identified by our method.

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Bibliographic Details
Published in:Computerized medical imaging and graphics 2017-06, Vol.58, p.62-74
Main Authors: Oh, Jihun, Kim, Gyehyun, Lee, Jaesung, Cheon, Minsu, Park, Yongsup, Kim, Sewon, Yi, Jonghyon, Lee, Ho Yun
Format: Article
Language:English
Subjects:
Automation
Bone cancer
Bone metastases
Bone Neoplasms - diagnostic imaging
Bones
Breast cancer
Cancer
Change detection
Chest
Computed tomography
False alarms
Follow-up CT scan
Humans
Image contrast
Image detection
Internal Medicine
Lesions
Longitudinal CT scans
Metastases
Metastasis
Morbidity
Neoplasm Metastasis - diagnostic imaging
Noise reduction
Other
Patients
Quantitative imaging
Registration
Ribs - diagnostic imaging
Sensitivity
Sensitivity and Specificity
Spine
Spine - diagnostic imaging
Sternum
Sternum - diagnostic imaging
Subtraction
Tomography, X-Ray Computed - methods
Warping
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Description
Summary:Highlights • Sclerotic and lytic bone metastases are quantified in spine, ribs, and sternum. • The volumes registered by weighted-Demons and symmetric warping are subtracted. • Many metastases missed by radiologists are identified by our method.
ISSN:0895-6111
1879-0771
DOI:10.1016/j.compmedimag.2016.11.007