Cell mechanotransduction: Stretch to express

Forces applied to the cell surface induce stretching of the chromatin in the nucleus and a rapid increase in gene expression.

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Bibliographic Details
Published in:Nature materials 2016-11, Vol.15 (12), p.1227-1229
Main Authors: Kirby, Tyler J, Lammerding, Jan
Format: Article
Language:English
Subjects:
Cells, Cultured
Cellular biology
Chromatin
Gene expression
Mechanotransduction, Cellular
Stress, Mechanical
Online Access:Get full text
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Description
Summary:Forces applied to the cell surface induce stretching of the chromatin in the nucleus and a rapid increase in gene expression.
ISSN:1476-1122
1476-4660
DOI:10.1038/nmat4809