Safety and efficacy of coil embolization of the septal perforator for septal ablation in patients with hypertrophic obstructive cardiomyopathy

Objective The objective of this study was to evaluate safety, efficacy, and durability of coil embolization of the major septal perforator of the left anterior descending coronary artery in patients with hypertrophic obstructive cardiomyopathy (HOCM). Background The long‐term effect of coil emboliza...

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Bibliographic Details
Published in:Catheterization and cardiovascular interventions 2016-11, Vol.88 (6), p.971-977
Main Authors: Guerrero, Israel, Dhoble, Abhijeet, Fasulo, Mark, Denktas, Ali E., Sami, Shehzad, Choi, Sangbum, Balan, Prakash, Arain, Salman A., Smalling, Richard W.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
alcohol septal ablation
Cardiomyopathy, Hypertrophic - diagnosis
Cardiomyopathy, Hypertrophic - surgery
Catheter Ablation - methods
coil embolization
Coronary Vessels - diagnostic imaging
Coronary Vessels - surgery
Echocardiography
Embolization, Therapeutic - instrumentation
Equipment Design
Female
Heart Septum - diagnostic imaging
Heart Septum - surgery
Humans
hypertrophic obstructive cardiomyopathy
Male
Middle Aged
myectomy
Time Factors
Treatment Outcome
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Summary:Objective The objective of this study was to evaluate safety, efficacy, and durability of coil embolization of the major septal perforator of the left anterior descending coronary artery in patients with hypertrophic obstructive cardiomyopathy (HOCM). Background The long‐term effect of coil embolization therapy in HOCM patients is not well defined. Methods We evaluated 24 symptomatic HOCM patients in a single center who underwent coil embolization of the septal perforator artery(ies). Results Twenty‐four patients on optimal medical therapy presented with NYHA functional class III (75%) or IV (25%) underwent the procedure. The procedure was successful in 22 patients, with significant reduction in left ventricular outflow tract (LVOT) gradient. The functional class significantly improved to class I (54.2%) or II (41.7%) (P 
ISSN:1522-1946
1522-726X
DOI:10.1002/ccd.26668