Hemophagocytic Syndrome due to Leishmania Infection Diagnosed with Immunofluorescence Antibody Test

Leishmaniasis is a reticuloendothelial system disease that mostly observed before the age of 5. Visceral infection causes long-standing fever, weight loss, weakness, pancytopenia, and hepatosplenomegaly. Leishmania infantum is responsible for visceral leishmaniasis (VL) in Turkey. We present a case...

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Bibliographic Details
Published in:Türkiye parazitolojii dergisi 2016-09, Vol.40 (3), p.163-165
Main Authors: Sarbay, Hakan, Balcı, Yasemin Işık, Güler, Selin, Türk, Meral, Akın, Mehmet, Polat, Aziz
Format: Article
Language:English
Subjects:
Child
Diagnosis, Differential
Fever - etiology
Fluorescent Antibody Technique
Gastrointestinal Hemorrhage - etiology
Humans
Leishmania infantum - immunology
Leishmaniasis, Visceral - complications
Leishmaniasis, Visceral - diagnosis
Male
Syndrome
Turkey
Weight Loss
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Summary:Leishmaniasis is a reticuloendothelial system disease that mostly observed before the age of 5. Visceral infection causes long-standing fever, weight loss, weakness, pancytopenia, and hepatosplenomegaly. Leishmania infantum is responsible for visceral leishmaniasis (VL) in Turkey. We present a case of hemophagocytic syndrome due to Leishmania infection diagnosed with an immunofluorescence antibody test (IFAT). Leishmania amastigotes were not observed on bone marrow aspiration. We consider that IFAT is very important for parasite detection in the diagnosis of VL in children, particularly when amastigotes are not obtained on bone marrow aspiration.
ISSN:1300-6320
2146-3077
DOI:10.5152/tpd.2016.4692