Novel carbazole-based two-photon photosensitizer for efficient DNA photocleavage in anaerobic condition using near-infrared light

Two novel carbazole derivatives, BMEPC and BMEMC, were designed, synthesized and first reported as two-photon photosensitizers for DNA photodamage, which showed efficient DNA photocleavage ability under near-infrared light exposure viaa two-photon process in anaerobic condition.

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Bibliographic Details
Published in:RSC advances 2015-01, Vol.5 (1), p.770-774
Main Authors: Zheng, Yong-Chao, Zheng, Mei-Ling, Li, Ke, Chen, Shu, Zhao, Zhen-Sheng, Wang, Xue-Song, Duan, Xuan-Ming
Format: Article
Language:English
Subjects:
Anaerobic conditions
Carbazoles
Deoxyribonucleic acid
Derivatives
Exposure
Synthesis
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Description
Summary:Two novel carbazole derivatives, BMEPC and BMEMC, were designed, synthesized and first reported as two-photon photosensitizers for DNA photodamage, which showed efficient DNA photocleavage ability under near-infrared light exposure viaa two-photon process in anaerobic condition.
ISSN:2046-2069
2046-2069
DOI:10.1039/c4ra11133h