Engineering Genes with CRISPR-Cas9

While parties are warring over CRISPR-Cas9 patents, other CRISPR discoveries and innovations have continued to surface. Recently, a new Cas protein called Cpfl has risen to prominence and may perform better than Cas9 (42). In contrast to Cas9, Cpfl can readily process multiple crRNAs from the CRISPR...

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Bibliographic Details
Published in:Chemical engineering progress 2016-09, Vol.112 (9), p.36-36
Main Authors: Luo, Michelle L, Beisel, Chase L
Format: Article
Language:English
Subjects:
Archaea
Bacteria
Chemical engineering
CRISPR
Deoxyribonucleic acid
Disease
DNA
Epigenetics
Ethics
Gene expression
Genetic disorders
Genetic engineering
Genetic modification
Genomes
Immune systems
Inventions
Mutation
Proteins
R&D
Research & development
Researchers
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Description
Summary:While parties are warring over CRISPR-Cas9 patents, other CRISPR discoveries and innovations have continued to surface. Recently, a new Cas protein called Cpfl has risen to prominence and may perform better than Cas9 (42). In contrast to Cas9, Cpfl can readily process multiple crRNAs from the CRISPR array and create cleavage products with "sticky ends," which may allow for easier modification of targeted DNA.
ISSN:0360-7275
1945-0710