Two new triterpenoids from the roots of Pinus densiflora

Chemical investigation of the roots of Pinus densiflora led to the isolation of two new triterpenoids, (24S)-3β-methoxy-24,25-epoxy-lanost-9(11)-ene (1) and 29-acetoxy-3α-methoxyserrat-14-en-21α-ol (2), together with three known serratene-type triterpenoids (3-5) and four known diterpenoids (6-9). T...

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Bibliographic Details
Published in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2017-03, Vol.81 (3), p.449-452
Main Authors: Otaka, Junnosuke, Komatsu, Masabumi, Miyazaki, Yasumasa, Futamura, Yushi, Osada, Hiroyuki
Format: Article
Language:English
Subjects:
Anti-Infective Agents - chemistry
Anti-Infective Agents - pharmacology
Antineoplastic Agents, Phytogenic - chemistry
Antineoplastic Agents, Phytogenic - pharmacology
Drug Evaluation, Preclinical - methods
Drug Screening Assays, Antitumor - methods
HeLa Cells - drug effects
Humans
Magnetic Resonance Spectroscopy
Molecular Structure
Pinaceae
Pinus - chemistry
Pinus densiflora
Plant Roots - chemistry
roots
Triterpenes - chemistry
Triterpenes - isolation & purification
Triterpenes - pharmacology
triterpenoid
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Summary:Chemical investigation of the roots of Pinus densiflora led to the isolation of two new triterpenoids, (24S)-3β-methoxy-24,25-epoxy-lanost-9(11)-ene (1) and 29-acetoxy-3α-methoxyserrat-14-en-21α-ol (2), together with three known serratene-type triterpenoids (3-5) and four known diterpenoids (6-9). Their structures were determined by spectroscopic analyses.
ISSN:0916-8451
1347-6947
DOI:10.1080/09168451.2016.1263149