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Multi-color polymer pen lithography for oligonucleotide arrays

Multi-color patterning by polymer pen lithography (PPL) was used to fabricate covalently immobilized fluorophore and oligonucleotide arrays with up to five different components. The oligonucleotide arrays offer a virtually unlimited inventory of orthogonal binding tags for self-assembly of proteins...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (83), p.12310-12313
Main Authors: Kumar, R, Weigel, S, Meyer, R, Niemeyer, C M, Fuchs, H, Hirtz, M
Format: Article
Language:English
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Summary:Multi-color patterning by polymer pen lithography (PPL) was used to fabricate covalently immobilized fluorophore and oligonucleotide arrays with up to five different components. The oligonucleotide arrays offer a virtually unlimited inventory of orthogonal binding tags for self-assembly of proteins as demonstrated by use of the arrays to monitor cell-protein interactions of MCF7 cells.
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc07087f