An extremely rapid-response fluorescent probe for hydrogen peroxide and its application in living cells

A turn-on fluorescence probe ACF for rapid detection of H 2 O 2 was constructed. The probe utilized a 2-(azidomethyl)benzoyl group as a new reaction site, which exhibited a rapid response to H 2 O 2 with a 118-fold fluorescence enhancement within 5 min. The biological application of ACF was confirme...

Full description

Saved in:
Bibliographic Details
Published in:RSC advances 2016-01, Vol.6 (92), p.8994-89943
Main Authors: Zhan, Fuxu, Yang, Qian, Wang, Qiufen, Zhang, Qilong, Zhuang, Zhiyuan, Feng, Xue, Zhang, Guangyou, Zheng, Gengxiu
Format: Article
Language:English
Subjects:
Cells (biology)
Fluorescence
Hydrogen peroxide
Imaging
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A turn-on fluorescence probe ACF for rapid detection of H 2 O 2 was constructed. The probe utilized a 2-(azidomethyl)benzoyl group as a new reaction site, which exhibited a rapid response to H 2 O 2 with a 118-fold fluorescence enhancement within 5 min. The biological application of ACF was confirmed by fluorescence imaging H 2 O 2 in living cells. An extremely rapid-response fluorescent probe for H 2 O 2 was constructed for monitoring the H 2 O 2 levels in biological processes.
ISSN:2046-2069
2046-2069
DOI:10.1039/c6ra12984f