Long- and short-term diabetes Mellitus type 1 modify young and elder rat salivary glands morphology

Highlights • Diabetes Mellitus (DM) increased laminin deposition on salivary glands in rats. • The effect of the laminin deposition was similar to the kidney. • Laminin deposition increased during the aging processing in non-diabetic rats. • Old non-diabetic rats had similar laminin deposition than...

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Bibliographic Details
Published in:Archives of oral biology 2017-01, Vol.73, p.40-47
Main Authors: Monteiro, M.M, D’Epiro, T.T.S, Bernardi, L, Fossati, A.C.M, Santos, M.F, Lamers, M.L., PhD
Format: Article
Language:English
Subjects:
Advanced Basic Science
Age Factors
Aging
Animals
Dentistry
Diabetes Mellitus, Type 1 - metabolism
Hyperglycemia
Immunoenzyme Techniques
Laminin
Laminin - metabolism
Male
Parotid
Rats
Rats, Wistar
Salivary Glands - metabolism
Submandibular gland
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Summary:Highlights • Diabetes Mellitus (DM) increased laminin deposition on salivary glands in rats. • The effect of the laminin deposition was similar to the kidney. • Laminin deposition increased during the aging processing in non-diabetic rats. • Old non-diabetic rats had similar laminin deposition than young rats with 30 DM.
ISSN:0003-9969
1879-1506
DOI:10.1016/j.archoralbio.2016.08.028