Enkephalin and neuropeptide-Y interaction in the intergeniculate leaflet network, a part of the mammalian biological clock

Highlights • Enkephalin and GABA are the major internal neurotransmitters of the IGL network. • Both NPY-positive and -negative neurons are postsynaptically hyperpolarized by ENK. • The μ opioid receptors are predominantly present on the IGL neurons. • Enkephalin modulates synaptic transmission in b...

Full description

Saved in:
Bibliographic Details
Published in:Neuroscience 2017-02, Vol.343, p.10-20
Main Authors: Palus, K, Chrobok, L, Kepczynski, M, Lewandowski, M.H
Format: Article
Language:English
Subjects:
Animals
Biological Clocks - drug effects
Biological Clocks - physiology
enkephalin
Enkephalins - administration & dosage
Enkephalins - metabolism
Excitatory Postsynaptic Potentials - drug effects
Excitatory Postsynaptic Potentials - physiology
gamma-Aminobutyric Acid - metabolism
Glutamic Acid - metabolism
Immunohistochemistry
Inhibitory Postsynaptic Potentials - drug effects
Inhibitory Postsynaptic Potentials - physiology
intergeniculate leaflet
Male
Miniature Postsynaptic Potentials - drug effects
Miniature Postsynaptic Potentials - physiology
Neurology
Neurons - cytology
Neurons - drug effects
Neurons - metabolism
neuropeptide Y
Neuropeptide Y - metabolism
Neurotransmitter Agents - administration & dosage
patch clamp
Patch-Clamp Techniques
Rats, Wistar
synaptic transmission
Synaptic Transmission - drug effects
Synaptic Transmission - physiology
Thalamic Nuclei - cytology
Thalamic Nuclei - drug effects
Thalamic Nuclei - metabolism
Tissue Culture Techniques
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Enkephalin and GABA are the major internal neurotransmitters of the IGL network. • Both NPY-positive and -negative neurons are postsynaptically hyperpolarized by ENK. • The μ opioid receptors are predominantly present on the IGL neurons. • Enkephalin modulates synaptic transmission in both NPY-positive and enkephalinergic IGL neurons.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2016.11.034