Application of a framework for the selection of an appropriate occupational exposure limit for manganese

[Display omitted] •Manganese occupational exposure limits (OELs) vary among organizations.•Guidance is provided for the selection of relevant and reliable OELs for manganese.•Three recent OELs were found to be quantitatively similar and equally reliable.•Similarities in the differently-derived OELs...

Full description

Saved in:
Bibliographic Details
Published in:Neurotoxicology (Park Forest South) 2017-01, Vol.58, p.249-256
Main Authors: Deveau, Michelle, Maier, Andrew, Krewski, Daniel
Format: Article
Language:English
Subjects:
Benchmarks
Decision making
Exposure
Exposure limits
Health risks
Humans
Manganese
Manganese - analysis
Manganese - toxicity
Manganese compounds
Neurotoxicity
Occupational exposure
Occupational Exposure - analysis
Occupational exposure limit
Occupational Health
Occupational hygiene
Organizations
Risk Assessment
Risk management
Selection framework
Threshold limit value
Threshold Limit Values
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[Display omitted] •Manganese occupational exposure limits (OELs) vary among organizations.•Guidance is provided for the selection of relevant and reliable OELs for manganese.•Three recent OELs were found to be quantitatively similar and equally reliable.•Similarities in the differently-derived OELs increases confidence in recent values. Occupational exposure limits (OELs) serve as benchmarks for the interpretation of workplace exposures within a health risk context. Different organizations derive OELs for many chemicals, including manganese. OELs recommended by different organizations can vary quantitatively, which can present a challenge to occupational hygienists or other risk managers that need to select a value for decision-making purposes. In this article, we illustrate the application of a previously-developed OEL selection framework to demonstrate the decisions that would be required to select the most appropriate OEL for various manganese exposure scenarios. The framework helped to identify the need to focus an evaluation on three quantitatively similar values—the ACGIH TLV, SCOEL IOELV, and DFG MAK. These values were compared with regulatory standards and considered for their relevance and reliability. The OEL selection framework was a useful tool in guiding the selection process for manganese OELs.
ISSN:0161-813X
1872-9711
DOI:10.1016/j.neuro.2016.09.014