Software performance in segmenting ground-glass and solid components of subsolid nodules in pulmonary adenocarcinomas

Objective To evaluate the performance of software in segmenting ground-glass and solid components of subsolid nodules in pulmonary adenocarcinomas. Method Seventy-three pulmonary adenocarcinomas manifesting as subsolid nodules were included. Two radiologists measured the maximal axial diameter of th...

Full description

Saved in:
Bibliographic Details
Published in:European radiology 2016-12, Vol.26 (12), p.4465-4474
Main Authors: Cohen, Julien G., Goo, Jin Mo, Yoo, Roh-Eul, Park, Chang Min, Lee, Chang Hyun, van Ginneken, Bram, Chung, Doo Hyun, Kim, Young Tae
Format: Article
Language:English
Subjects:
Adenocarcinoma - diagnostic imaging
Adenocarcinoma of Lung
Adult
Aged
Cancer
Chest
Diagnostic Radiology
Female
Humans
Image Processing, Computer-Assisted - methods
Imaging
Internal Medicine
Interventional Radiology
Lung - diagnostic imaging
Lung Neoplasms - diagnostic imaging
Male
Mediastinum - diagnostic imaging
Medical research
Medical schools
Medicine
Medicine & Public Health
Middle Aged
Neuroradiology
Pathology
Performance evaluation
Radiologists
Radiology
Retrospective Studies
Software
Solitary Pulmonary Nodule - diagnostic imaging
Thoracic surgery
Tomography, X-Ray Computed
Ultrasound
University colleges
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective To evaluate the performance of software in segmenting ground-glass and solid components of subsolid nodules in pulmonary adenocarcinomas. Method Seventy-three pulmonary adenocarcinomas manifesting as subsolid nodules were included. Two radiologists measured the maximal axial diameter of the ground-glass components on lung windows and that of the solid components on lung and mediastinal windows. Nodules were segmented using software by applying five (-850 HU to -650 HU) and nine (-130 HU to -500 HU) attenuation thresholds. We compared the manual and software measurements of ground-glass and solid components with pathology measurements of tumour and invasive components. Results Segmentation of ground-glass components at a threshold of -750 HU yielded mean differences of +0.06 mm ( p  = 0.83, 95 % limits of agreement, 4.51 to 4.67) and -2.32 mm ( p  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-016-4317-3