Diffuse HIV-associated seborrheic dermatitis – a case series

Seborrheic dermatitis (SD) is reported to have distinct clinical and histologic presentations in patients with HIV infection. Here we present 20 cases to further define some of these unique characteristics. Common features include erythematous, scaly papules, and plaques involving areas beyond the t...

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Bibliographic Details
Published in:International journal of STD & AIDS 2016-12, Vol.27 (14), p.1342-1345
Main Authors: Forrestel, Amy K, Kovarik, Carrie L, Mosam, Anisa, Gupta, Deepti, Maurer, Toby A, Micheletti, Robert G
Format: Article
Language:English
Subjects:
Administration, Topical
Adrenal Cortex Hormones - administration & dosage
Adrenal Cortex Hormones - therapeutic use
Adult
AIDS-Related Opportunistic Infections - diagnosis
AIDS-Related Opportunistic Infections - drug therapy
AIDS-Related Opportunistic Infections - immunology
AIDS/HIV
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - therapeutic use
CD4 Lymphocyte Count
Dermatitis, Seborrheic - complications
Dermatitis, Seborrheic - diagnosis
Dermatitis, Seborrheic - drug therapy
Dermatologic Agents - administration & dosage
Dermatologic Agents - therapeutic use
Female
HIV Infections - complications
HIV Infections - immunology
Humans
Lentivirus
Male
Middle Aged
Retroviridae
Treatment Outcome
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Description
Summary:Seborrheic dermatitis (SD) is reported to have distinct clinical and histologic presentations in patients with HIV infection. Here we present 20 cases to further define some of these unique characteristics. Common features include erythematous, scaly papules, and plaques involving areas beyond the typical seborrheic distribution; thick, greasy scale on the scalp; and an increased frequency of erythroderma. Histologically, there is widespread parakeratosis, spongiosis, and necrotic keratinocytes. Treatment is often difficult, requiring prolonged use of oral and topical antifungals and corticosteroids as well as antibiotics for bacterial superinfection. SD with these features represents a marker for HIV infection and can aid in early diagnosis.
ISSN:0956-4624
1758-1052
DOI:10.1177/0956462416641816