Right atrial lead fixation type and lead position are associated with significant variation in complications

• Published in: Journal of interventional cardiac electrophysiology 2016-12, Vol.47 (3), p.313-319
• Main Authors: Witt, Chance M., Lenz, Charles J., Shih, Henry H., Ebrille, Elisa, Rosenbaum, Andrew N., Aung, Htin, van Zyl, Martin, Manocha, Kevin K., Deshmukh, Abhishek J., Hodge, David O., Mulpuru, Siva K., Cha, Yong-Mei, Espinosa, Raul E., Asirvatham, Samuel J., McLeod, Christopher J.
• Format: Article
• Language: English
• Subjects: Aged; Cardiac Resynchronization Therapy Devices - utilization; Cardiology; Causality; Comorbidity; Device Removal - utilization; Electrodes, Implanted - classification; Electrodes, Implanted - utilization; Female; Foreign-Body Migration - epidemiology; Humans; Male; Medicine; Medicine & Public Health; Minnesota - epidemiology; Pericardial Effusion - epidemiology; Pericardial Effusion - surgery; Pericardiocentesis - utilization; Prevalence; Prosthesis Implantation; Retrospective Studies; Treatment Outcome
• ISSN: 1383-875X; 1572-8595
• DOI: 10.1007/s10840-016-0181-y

Purpose Optimal atrial pacemaker lead position and fixation mechanism have not been determined with regard to effect on complications. We aimed to determine the association between atrial lead-related complications and varying atrial lead tip positions and lead fixation mechanisms. Methods All patients who underwent dual-chamber pacemaker implant between 2004 and 2014 were retrospectively reviewed for atrial lead tip position and fixation type. Lead-related complications were assessed by electronic medical record review. Complication rates were compared at 1 year by chi-square analysis and at 5 years using a Kaplan-Meier analysis. Results During the study period, 3451 patients (mean age 73.9, 53.4 % male) underwent dual-chamber pacemaker placement. Active fixation leads were associated with a higher incidence of pericardial effusion (81 (2.9 %) vs. 6 (1.0 %), p  = 0.005) and pericardiocentesis (46 (1.6 %) vs. 2 (0.3 %), p  = 0.01) at 1 year compared to passive fixation leads. There was no difference in overall complication rates by fixation type (161 (5.7 %) vs. 29 (4.6 %), p  = 0.26). Low atrial septal lead tip position was associated with a higher rate of lead dislodgement (10 (15.2 %)) compared to appendage (46 (1.6 %)), free wall (10 (2.1 %)), or high atrial septal (2 (4.7 %)) positions ( p