Quality of recovery from anesthesia of patients undergoing balanced or total intravenous general anesthesia. Prospective randomized clinical trial

• Published in: Journal of clinical anesthesia 2016-12, Vol.35, p.369-375
• Main Authors: Moro, Eduardo Toshiyuki, MD, PhD, Leme, Fábio Caetano Oliveira, MD, Noronha, Bernardo Roveda, MD, Saraiva, Gustavo Farinha Pinto, de Matos Leite, Nathália Vianna, Navarro, Laís Helena Camacho, MD, PhD
• Format: Article
• Language: English
• Subjects: Adult; Anesthesia; Anesthesia & Perioperative Care; Anesthesia Recovery Period; Anesthesia, General - methods; Anesthesia, Inhalation - methods; Anesthesia, Intravenous - methods; Clinical trials; Double-Blind Method; Female; Humans; Inhalation anesthesia; Intravenous anesthesia; Male; Medical personnel; Methyl Ethers; Pain; Pain Medicine; Patient satisfaction; Physiology; Piperidines; Propofol; Prospective Studies; Quality; Quality measures; Questionnaire; Questionnaires; Recovery (Medical); Recovery from anesthesia; Surgery; Vomiting
• ISSN: 0952-8180; 1873-4529
• DOI: 10.1016/j.jclinane.2016.08.022

Abstract Study objectives The aim of the present study was to assess the quality of recovery from anesthesia of patients subjected to otorhinolaryngological (ORL) surgery under balanced or total intravenous general anesthesia by means of Quality of Recovery-40 (QoR-40) questionnaire. Design Prospective randomized clinical trial. Setting The setting is at an operating room, a postoperative recovery area, and a hospital ward. Patients One-hundred thirty American Society of Anesthesiologists physical status I or II patients scheduled to undergo general anesthesia for ORL interventions under remifentanil, in combination with sevoflurane (balanced technique) or propofol (total intravenous anesthesia). Measurements Occurrence of nausea, vomiting, body temperature less than 36°C, and length of stay in the postanesthesia care unit were recorded. The QoR-40 was administered by an investigator blind to group allocation 24 hours after surgery. The quality of recovery, as assessed by the score on the QoR-40, was compared between the groups. Main results There is no difference regarding the QoR-40 score among intravenous and inhalation anesthesia groups (190.5 vs 189.5, respectively; P = .33). Similarly, among the 5 dimensions of the QoR-40, the scores were comparable between the groups. Incidence of hypothermia ( P = .58), nauseas or vomits ( P = .39), and length of surgery ( P = .16) were similar among groups. The evaluation of pain intensity ( P = .80) and dose of morphine use in the postanesthesia care unit ( P = .4) was also comparable between groups. Conclusions The quality of recovery from anesthesia assessed based on the patients' perception did not differ between the ones subjected to either inhalation or intravenous general anesthesia for ORL surgery based on QoR-40 questionnaire assessment.