Renal impairment and coronary collaterals in patients with acute coronary syndrome

• Published in: Herz 2014-05, Vol.39 (3), p.379-383
• Main Authors: Duran, M., Uysal, O.K., Gunebakmaz, O., Yilmaz, Y., Vatankulu, M.A., Turfan, M., Duran, A.O., Ornek, E., Cetin, M., Murat, S.N., Kaya, M.G.
• Format: Article
• Language: English
• Subjects: Acute Coronary Syndrome - diagnostic imaging; Acute Coronary Syndrome - epidemiology; Cardiology; Causality; Collateral Circulation; Comorbidity; Coronary Vessels - diagnostic imaging; e-Herz: Original article; Female; Humans; Incidence; Internal Medicine; Kidney Diseases - diagnostic imaging; Kidney Diseases - epidemiology; Male; Medicine; Medicine & Public Health; Middle Aged; Neovascularization, Pathologic - diagnostic imaging; Neovascularization, Pathologic - epidemiology; Radiography; Risk Assessment; Turkey - epidemiology
• ISSN: 0340-9937; 1615-6692
• DOI: 10.1007/s00059-013-3823-1

Objective We aimed to elucidate the relationship between mild-to-moderate renal impairment and the development of coronary collateral vessels (CCV) in patients with acute coronary syndrome (ACS). Methods We enrolled 461 patients with ACS who underwent coronary angiography for the first time. The development of CCV was assessed with the Rentrop score. Kidney function was classified according to the estimated glomerular filtration rate (eGFR). The Gensini score was used to show the extent of atherosclerosis. Results The mean eGFR value was 89.9 ± 24.3 U/l for patients with no development of collaterals and 82.7 ± 20.5 for patients who had CCV. The mean age was 59 ± 11 years and 349 patients (75.7 %) were male. Rentrop classifications 1-2-3 (presence of CCV) were determined in 222 (48.1 %) patients. The presence of CCV was significantly associated with low levels of eGFR (p = 0.001), increased serum creatinine levels (p = 0.034), high levels of serum albumin (0.036), and the Gensini score (p