Loading…
Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates
Background Cephalosporins are one of the most commonly used antibiotics in United Arab Emirates (UAE). Few studies have been carried out to evaluate the antibiotic utilization pattern in UAE in spite of the obvious increase in cephalosporins resistance during the past decade. Objective To assess the...
Saved in:
Published in: | International journal of clinical pharmacy 2016-12, Vol.38 (6), p.1367-1371 |
---|---|
Main Authors: | , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003 |
---|---|
cites | cdi_FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003 |
container_end_page | 1371 |
container_issue | 6 |
container_start_page | 1367 |
container_title | International journal of clinical pharmacy |
container_volume | 38 |
creator | Abou-Shaaban, Mohammad Ali, Areeg Anwer Rao, Padma G. M. Majid, Asif |
description | Background
Cephalosporins are one of the most commonly used antibiotics in United Arab Emirates (UAE). Few studies have been carried out to evaluate the antibiotic utilization pattern in UAE in spite of the obvious increase in cephalosporins resistance during the past decade.
Objective
To assess the prescriptions pattern of cephalosporins among physicians at a secondary care hospital in Ras Al Khaimah, UAE.
Method
This observational prospective study was carried out during October 2013 to April 2014. The data of in patients were documented in the predesigned patient profile form and was analyzed for patient’s, drug’s and drug’s therapy related parameters.
Results
The 3rd generation cephalosporins constituted 83.6 % of the prescriptions, with ceftriaxone being the most commonly used one (81.1 %). They were mainly prescribed for the treatment of the lower respiratory tract infections (60.2 %). Seven (3.5 %) different ADRs linked to cephalosporin use were observed ranging from oral thrush to clostridium difficile infection. A total of 1039 antimicrobial and nonantimicrobial medications were prescribed concomitantly with cephalosporins.
Conclusion
The 3rd generation cephalosporins were commonly prescribed by parenteral route. Thus, there is a strong need for rationalizing their use to preserve their efficacy and prevent the development of resistance in the region. |
doi_str_mv | 10.1007/s11096-016-0392-4 |
format | article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1850781561</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1850781561</sourcerecordid><originalsourceid>FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003</originalsourceid><addsrcrecordid>eNqNkUtLxDAUhYMoKjo_wI0E3Lip3pvm0VmKbxDcOFtDmqYa6TRj0ir6680wKiIIBkIC57vn5uYQsodwhADqOCHCVBaAeZdTVvA1ss0YQqEU4vr3HcotMknpCfLikqHgm2SLqQoVKrZN7s_i-EDHwXf-3Qw-9DS6F-9eaWipdYtH04W0CNH3ifqeGpqcDX1j4hu1Jjr6mFU_mG4pzno_uIaeRFPT87mPZnBpl2y0pktu8nnukNnF-d3pVXFze3l9enJTWA5iKKoaayVBQIutgdpIrtAwaXlbQVubKS9RWmkUE6KuGoON4JyDYtw2smUA5Q45XPkuYngeXRr03Cfrus70LoxJYyUgzywk_gMtFTDBUWX04Bf6FMbY50Eyxcv8GqlYpnBF2RhSiq7Vi-jn-Ys0gl5GpVdR6RyVXkalea7Z_3Qe67lrviu-gskAWwEpS_2Diz9a_-n6AS4-nIg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1843255672</pqid></control><display><type>article</type><title>Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates</title><source>Springer Nature</source><creator>Abou-Shaaban, Mohammad ; Ali, Areeg Anwer ; Rao, Padma G. M. ; Majid, Asif</creator><creatorcontrib>Abou-Shaaban, Mohammad ; Ali, Areeg Anwer ; Rao, Padma G. M. ; Majid, Asif</creatorcontrib><description>Background
Cephalosporins are one of the most commonly used antibiotics in United Arab Emirates (UAE). Few studies have been carried out to evaluate the antibiotic utilization pattern in UAE in spite of the obvious increase in cephalosporins resistance during the past decade.
Objective
To assess the prescriptions pattern of cephalosporins among physicians at a secondary care hospital in Ras Al Khaimah, UAE.
Method
This observational prospective study was carried out during October 2013 to April 2014. The data of in patients were documented in the predesigned patient profile form and was analyzed for patient’s, drug’s and drug’s therapy related parameters.
Results
The 3rd generation cephalosporins constituted 83.6 % of the prescriptions, with ceftriaxone being the most commonly used one (81.1 %). They were mainly prescribed for the treatment of the lower respiratory tract infections (60.2 %). Seven (3.5 %) different ADRs linked to cephalosporin use were observed ranging from oral thrush to clostridium difficile infection. A total of 1039 antimicrobial and nonantimicrobial medications were prescribed concomitantly with cephalosporins.
Conclusion
The 3rd generation cephalosporins were commonly prescribed by parenteral route. Thus, there is a strong need for rationalizing their use to preserve their efficacy and prevent the development of resistance in the region.</description><identifier>ISSN: 2210-7703</identifier><identifier>EISSN: 2210-7711</identifier><identifier>DOI: 10.1007/s11096-016-0392-4</identifier><identifier>PMID: 27817172</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Adolescent ; Adult ; Aged ; Anti-Bacterial Agents ; Antibiotics ; Cephalosporins ; Clostridium difficile ; Drug therapy ; Drug use ; Drug Utilization Review - methods ; Female ; Hospitals ; Humans ; Internal Medicine ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Pharmacy ; Prospective Studies ; Respiratory diseases ; Secondary Care - standards ; Secondary Care - trends ; Secondary Care Centers - standards ; Secondary Care Centers - trends ; Short Research Report ; United Arab Emirates - epidemiology ; Young Adult</subject><ispartof>International journal of clinical pharmacy, 2016-12, Vol.38 (6), p.1367-1371</ispartof><rights>Springer International Publishing 2016</rights><rights>International Journal of Clinical Pharmacy is a copyright of Springer, 2016.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003</citedby><cites>FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27817172$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Abou-Shaaban, Mohammad</creatorcontrib><creatorcontrib>Ali, Areeg Anwer</creatorcontrib><creatorcontrib>Rao, Padma G. M.</creatorcontrib><creatorcontrib>Majid, Asif</creatorcontrib><title>Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates</title><title>International journal of clinical pharmacy</title><addtitle>Int J Clin Pharm</addtitle><addtitle>Int J Clin Pharm</addtitle><description>Background
Cephalosporins are one of the most commonly used antibiotics in United Arab Emirates (UAE). Few studies have been carried out to evaluate the antibiotic utilization pattern in UAE in spite of the obvious increase in cephalosporins resistance during the past decade.
Objective
To assess the prescriptions pattern of cephalosporins among physicians at a secondary care hospital in Ras Al Khaimah, UAE.
Method
This observational prospective study was carried out during October 2013 to April 2014. The data of in patients were documented in the predesigned patient profile form and was analyzed for patient’s, drug’s and drug’s therapy related parameters.
Results
The 3rd generation cephalosporins constituted 83.6 % of the prescriptions, with ceftriaxone being the most commonly used one (81.1 %). They were mainly prescribed for the treatment of the lower respiratory tract infections (60.2 %). Seven (3.5 %) different ADRs linked to cephalosporin use were observed ranging from oral thrush to clostridium difficile infection. A total of 1039 antimicrobial and nonantimicrobial medications were prescribed concomitantly with cephalosporins.
Conclusion
The 3rd generation cephalosporins were commonly prescribed by parenteral route. Thus, there is a strong need for rationalizing their use to preserve their efficacy and prevent the development of resistance in the region.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Anti-Bacterial Agents</subject><subject>Antibiotics</subject><subject>Cephalosporins</subject><subject>Clostridium difficile</subject><subject>Drug therapy</subject><subject>Drug use</subject><subject>Drug Utilization Review - methods</subject><subject>Female</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Pharmacy</subject><subject>Prospective Studies</subject><subject>Respiratory diseases</subject><subject>Secondary Care - standards</subject><subject>Secondary Care - trends</subject><subject>Secondary Care Centers - standards</subject><subject>Secondary Care Centers - trends</subject><subject>Short Research Report</subject><subject>United Arab Emirates - epidemiology</subject><subject>Young Adult</subject><issn>2210-7703</issn><issn>2210-7711</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqNkUtLxDAUhYMoKjo_wI0E3Lip3pvm0VmKbxDcOFtDmqYa6TRj0ir6680wKiIIBkIC57vn5uYQsodwhADqOCHCVBaAeZdTVvA1ss0YQqEU4vr3HcotMknpCfLikqHgm2SLqQoVKrZN7s_i-EDHwXf-3Qw-9DS6F-9eaWipdYtH04W0CNH3ifqeGpqcDX1j4hu1Jjr6mFU_mG4pzno_uIaeRFPT87mPZnBpl2y0pktu8nnukNnF-d3pVXFze3l9enJTWA5iKKoaayVBQIutgdpIrtAwaXlbQVubKS9RWmkUE6KuGoON4JyDYtw2smUA5Q45XPkuYngeXRr03Cfrus70LoxJYyUgzywk_gMtFTDBUWX04Bf6FMbY50Eyxcv8GqlYpnBF2RhSiq7Vi-jn-Ys0gl5GpVdR6RyVXkalea7Z_3Qe67lrviu-gskAWwEpS_2Diz9a_-n6AS4-nIg</recordid><startdate>20161201</startdate><enddate>20161201</enddate><creator>Abou-Shaaban, Mohammad</creator><creator>Ali, Areeg Anwer</creator><creator>Rao, Padma G. M.</creator><creator>Majid, Asif</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20161201</creationdate><title>Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates</title><author>Abou-Shaaban, Mohammad ; Ali, Areeg Anwer ; Rao, Padma G. M. ; Majid, Asif</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Anti-Bacterial Agents</topic><topic>Antibiotics</topic><topic>Cephalosporins</topic><topic>Clostridium difficile</topic><topic>Drug therapy</topic><topic>Drug use</topic><topic>Drug Utilization Review - methods</topic><topic>Female</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Pharmacy</topic><topic>Prospective Studies</topic><topic>Respiratory diseases</topic><topic>Secondary Care - standards</topic><topic>Secondary Care - trends</topic><topic>Secondary Care Centers - standards</topic><topic>Secondary Care Centers - trends</topic><topic>Short Research Report</topic><topic>United Arab Emirates - epidemiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abou-Shaaban, Mohammad</creatorcontrib><creatorcontrib>Ali, Areeg Anwer</creatorcontrib><creatorcontrib>Rao, Padma G. M.</creatorcontrib><creatorcontrib>Majid, Asif</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database (ProQuest)</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>International journal of clinical pharmacy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abou-Shaaban, Mohammad</au><au>Ali, Areeg Anwer</au><au>Rao, Padma G. M.</au><au>Majid, Asif</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates</atitle><jtitle>International journal of clinical pharmacy</jtitle><stitle>Int J Clin Pharm</stitle><addtitle>Int J Clin Pharm</addtitle><date>2016-12-01</date><risdate>2016</risdate><volume>38</volume><issue>6</issue><spage>1367</spage><epage>1371</epage><pages>1367-1371</pages><issn>2210-7703</issn><eissn>2210-7711</eissn><abstract>Background
Cephalosporins are one of the most commonly used antibiotics in United Arab Emirates (UAE). Few studies have been carried out to evaluate the antibiotic utilization pattern in UAE in spite of the obvious increase in cephalosporins resistance during the past decade.
Objective
To assess the prescriptions pattern of cephalosporins among physicians at a secondary care hospital in Ras Al Khaimah, UAE.
Method
This observational prospective study was carried out during October 2013 to April 2014. The data of in patients were documented in the predesigned patient profile form and was analyzed for patient’s, drug’s and drug’s therapy related parameters.
Results
The 3rd generation cephalosporins constituted 83.6 % of the prescriptions, with ceftriaxone being the most commonly used one (81.1 %). They were mainly prescribed for the treatment of the lower respiratory tract infections (60.2 %). Seven (3.5 %) different ADRs linked to cephalosporin use were observed ranging from oral thrush to clostridium difficile infection. A total of 1039 antimicrobial and nonantimicrobial medications were prescribed concomitantly with cephalosporins.
Conclusion
The 3rd generation cephalosporins were commonly prescribed by parenteral route. Thus, there is a strong need for rationalizing their use to preserve their efficacy and prevent the development of resistance in the region.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>27817172</pmid><doi>10.1007/s11096-016-0392-4</doi><tpages>5</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 2210-7703 |
ispartof | International journal of clinical pharmacy, 2016-12, Vol.38 (6), p.1367-1371 |
issn | 2210-7703 2210-7711 |
language | eng |
recordid | cdi_proquest_miscellaneous_1850781561 |
source | Springer Nature |
subjects | Adolescent Adult Aged Anti-Bacterial Agents Antibiotics Cephalosporins Clostridium difficile Drug therapy Drug use Drug Utilization Review - methods Female Hospitals Humans Internal Medicine Male Medicine Medicine & Public Health Middle Aged Pharmacy Prospective Studies Respiratory diseases Secondary Care - standards Secondary Care - trends Secondary Care Centers - standards Secondary Care Centers - trends Short Research Report United Arab Emirates - epidemiology Young Adult |
title | Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T02%3A55%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Drug%20utilization%20review%20of%20cephalosporins%20in%20a%20secondary%20care%20hospital%20in%20United%20Arab%20Emirates&rft.jtitle=International%20journal%20of%20clinical%20pharmacy&rft.au=Abou-Shaaban,%20Mohammad&rft.date=2016-12-01&rft.volume=38&rft.issue=6&rft.spage=1367&rft.epage=1371&rft.pages=1367-1371&rft.issn=2210-7703&rft.eissn=2210-7711&rft_id=info:doi/10.1007/s11096-016-0392-4&rft_dat=%3Cproquest_cross%3E1850781561%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1843255672&rft_id=info:pmid/27817172&rfr_iscdi=true |