Loading…

Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates

Background Cephalosporins are one of the most commonly used antibiotics in United Arab Emirates (UAE). Few studies have been carried out to evaluate the antibiotic utilization pattern in UAE in spite of the obvious increase in cephalosporins resistance during the past decade. Objective To assess the...

Full description

Saved in:
Bibliographic Details
Published in:International journal of clinical pharmacy 2016-12, Vol.38 (6), p.1367-1371
Main Authors: Abou-Shaaban, Mohammad, Ali, Areeg Anwer, Rao, Padma G. M., Majid, Asif
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003
cites cdi_FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003
container_end_page 1371
container_issue 6
container_start_page 1367
container_title International journal of clinical pharmacy
container_volume 38
creator Abou-Shaaban, Mohammad
Ali, Areeg Anwer
Rao, Padma G. M.
Majid, Asif
description Background Cephalosporins are one of the most commonly used antibiotics in United Arab Emirates (UAE). Few studies have been carried out to evaluate the antibiotic utilization pattern in UAE in spite of the obvious increase in cephalosporins resistance during the past decade. Objective To assess the prescriptions pattern of cephalosporins among physicians at a secondary care hospital in Ras Al Khaimah, UAE. Method This observational prospective study was carried out during October 2013 to April 2014. The data of in patients were documented in the predesigned patient profile form and was analyzed for patient’s, drug’s and drug’s therapy related parameters. Results The 3rd generation cephalosporins constituted 83.6 % of the prescriptions, with ceftriaxone being the most commonly used one (81.1 %). They were mainly prescribed for the treatment of the lower respiratory tract infections (60.2 %). Seven (3.5 %) different ADRs linked to cephalosporin use were observed ranging from oral thrush to clostridium difficile infection. A total of 1039 antimicrobial and nonantimicrobial medications were prescribed concomitantly with cephalosporins. Conclusion The 3rd generation cephalosporins were commonly prescribed by parenteral route. Thus, there is a strong need for rationalizing their use to preserve their efficacy and prevent the development of resistance in the region.
doi_str_mv 10.1007/s11096-016-0392-4
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1850781561</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1850781561</sourcerecordid><originalsourceid>FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003</originalsourceid><addsrcrecordid>eNqNkUtLxDAUhYMoKjo_wI0E3Lip3pvm0VmKbxDcOFtDmqYa6TRj0ir6680wKiIIBkIC57vn5uYQsodwhADqOCHCVBaAeZdTVvA1ss0YQqEU4vr3HcotMknpCfLikqHgm2SLqQoVKrZN7s_i-EDHwXf-3Qw-9DS6F-9eaWipdYtH04W0CNH3ifqeGpqcDX1j4hu1Jjr6mFU_mG4pzno_uIaeRFPT87mPZnBpl2y0pktu8nnukNnF-d3pVXFze3l9enJTWA5iKKoaayVBQIutgdpIrtAwaXlbQVubKS9RWmkUE6KuGoON4JyDYtw2smUA5Q45XPkuYngeXRr03Cfrus70LoxJYyUgzywk_gMtFTDBUWX04Bf6FMbY50Eyxcv8GqlYpnBF2RhSiq7Vi-jn-Ys0gl5GpVdR6RyVXkalea7Z_3Qe67lrviu-gskAWwEpS_2Diz9a_-n6AS4-nIg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1843255672</pqid></control><display><type>article</type><title>Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates</title><source>Springer Nature</source><creator>Abou-Shaaban, Mohammad ; Ali, Areeg Anwer ; Rao, Padma G. M. ; Majid, Asif</creator><creatorcontrib>Abou-Shaaban, Mohammad ; Ali, Areeg Anwer ; Rao, Padma G. M. ; Majid, Asif</creatorcontrib><description>Background Cephalosporins are one of the most commonly used antibiotics in United Arab Emirates (UAE). Few studies have been carried out to evaluate the antibiotic utilization pattern in UAE in spite of the obvious increase in cephalosporins resistance during the past decade. Objective To assess the prescriptions pattern of cephalosporins among physicians at a secondary care hospital in Ras Al Khaimah, UAE. Method This observational prospective study was carried out during October 2013 to April 2014. The data of in patients were documented in the predesigned patient profile form and was analyzed for patient’s, drug’s and drug’s therapy related parameters. Results The 3rd generation cephalosporins constituted 83.6 % of the prescriptions, with ceftriaxone being the most commonly used one (81.1 %). They were mainly prescribed for the treatment of the lower respiratory tract infections (60.2 %). Seven (3.5 %) different ADRs linked to cephalosporin use were observed ranging from oral thrush to clostridium difficile infection. A total of 1039 antimicrobial and nonantimicrobial medications were prescribed concomitantly with cephalosporins. Conclusion The 3rd generation cephalosporins were commonly prescribed by parenteral route. Thus, there is a strong need for rationalizing their use to preserve their efficacy and prevent the development of resistance in the region.</description><identifier>ISSN: 2210-7703</identifier><identifier>EISSN: 2210-7711</identifier><identifier>DOI: 10.1007/s11096-016-0392-4</identifier><identifier>PMID: 27817172</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Adolescent ; Adult ; Aged ; Anti-Bacterial Agents ; Antibiotics ; Cephalosporins ; Clostridium difficile ; Drug therapy ; Drug use ; Drug Utilization Review - methods ; Female ; Hospitals ; Humans ; Internal Medicine ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Pharmacy ; Prospective Studies ; Respiratory diseases ; Secondary Care - standards ; Secondary Care - trends ; Secondary Care Centers - standards ; Secondary Care Centers - trends ; Short Research Report ; United Arab Emirates - epidemiology ; Young Adult</subject><ispartof>International journal of clinical pharmacy, 2016-12, Vol.38 (6), p.1367-1371</ispartof><rights>Springer International Publishing 2016</rights><rights>International Journal of Clinical Pharmacy is a copyright of Springer, 2016.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003</citedby><cites>FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27817172$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Abou-Shaaban, Mohammad</creatorcontrib><creatorcontrib>Ali, Areeg Anwer</creatorcontrib><creatorcontrib>Rao, Padma G. M.</creatorcontrib><creatorcontrib>Majid, Asif</creatorcontrib><title>Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates</title><title>International journal of clinical pharmacy</title><addtitle>Int J Clin Pharm</addtitle><addtitle>Int J Clin Pharm</addtitle><description>Background Cephalosporins are one of the most commonly used antibiotics in United Arab Emirates (UAE). Few studies have been carried out to evaluate the antibiotic utilization pattern in UAE in spite of the obvious increase in cephalosporins resistance during the past decade. Objective To assess the prescriptions pattern of cephalosporins among physicians at a secondary care hospital in Ras Al Khaimah, UAE. Method This observational prospective study was carried out during October 2013 to April 2014. The data of in patients were documented in the predesigned patient profile form and was analyzed for patient’s, drug’s and drug’s therapy related parameters. Results The 3rd generation cephalosporins constituted 83.6 % of the prescriptions, with ceftriaxone being the most commonly used one (81.1 %). They were mainly prescribed for the treatment of the lower respiratory tract infections (60.2 %). Seven (3.5 %) different ADRs linked to cephalosporin use were observed ranging from oral thrush to clostridium difficile infection. A total of 1039 antimicrobial and nonantimicrobial medications were prescribed concomitantly with cephalosporins. Conclusion The 3rd generation cephalosporins were commonly prescribed by parenteral route. Thus, there is a strong need for rationalizing their use to preserve their efficacy and prevent the development of resistance in the region.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Anti-Bacterial Agents</subject><subject>Antibiotics</subject><subject>Cephalosporins</subject><subject>Clostridium difficile</subject><subject>Drug therapy</subject><subject>Drug use</subject><subject>Drug Utilization Review - methods</subject><subject>Female</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Middle Aged</subject><subject>Pharmacy</subject><subject>Prospective Studies</subject><subject>Respiratory diseases</subject><subject>Secondary Care - standards</subject><subject>Secondary Care - trends</subject><subject>Secondary Care Centers - standards</subject><subject>Secondary Care Centers - trends</subject><subject>Short Research Report</subject><subject>United Arab Emirates - epidemiology</subject><subject>Young Adult</subject><issn>2210-7703</issn><issn>2210-7711</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqNkUtLxDAUhYMoKjo_wI0E3Lip3pvm0VmKbxDcOFtDmqYa6TRj0ir6680wKiIIBkIC57vn5uYQsodwhADqOCHCVBaAeZdTVvA1ss0YQqEU4vr3HcotMknpCfLikqHgm2SLqQoVKrZN7s_i-EDHwXf-3Qw-9DS6F-9eaWipdYtH04W0CNH3ifqeGpqcDX1j4hu1Jjr6mFU_mG4pzno_uIaeRFPT87mPZnBpl2y0pktu8nnukNnF-d3pVXFze3l9enJTWA5iKKoaayVBQIutgdpIrtAwaXlbQVubKS9RWmkUE6KuGoON4JyDYtw2smUA5Q45XPkuYngeXRr03Cfrus70LoxJYyUgzywk_gMtFTDBUWX04Bf6FMbY50Eyxcv8GqlYpnBF2RhSiq7Vi-jn-Ys0gl5GpVdR6RyVXkalea7Z_3Qe67lrviu-gskAWwEpS_2Diz9a_-n6AS4-nIg</recordid><startdate>20161201</startdate><enddate>20161201</enddate><creator>Abou-Shaaban, Mohammad</creator><creator>Ali, Areeg Anwer</creator><creator>Rao, Padma G. M.</creator><creator>Majid, Asif</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20161201</creationdate><title>Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates</title><author>Abou-Shaaban, Mohammad ; Ali, Areeg Anwer ; Rao, Padma G. M. ; Majid, Asif</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Anti-Bacterial Agents</topic><topic>Antibiotics</topic><topic>Cephalosporins</topic><topic>Clostridium difficile</topic><topic>Drug therapy</topic><topic>Drug use</topic><topic>Drug Utilization Review - methods</topic><topic>Female</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Middle Aged</topic><topic>Pharmacy</topic><topic>Prospective Studies</topic><topic>Respiratory diseases</topic><topic>Secondary Care - standards</topic><topic>Secondary Care - trends</topic><topic>Secondary Care Centers - standards</topic><topic>Secondary Care Centers - trends</topic><topic>Short Research Report</topic><topic>United Arab Emirates - epidemiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abou-Shaaban, Mohammad</creatorcontrib><creatorcontrib>Ali, Areeg Anwer</creatorcontrib><creatorcontrib>Rao, Padma G. M.</creatorcontrib><creatorcontrib>Majid, Asif</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database (ProQuest)</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>ProQuest_Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>International journal of clinical pharmacy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abou-Shaaban, Mohammad</au><au>Ali, Areeg Anwer</au><au>Rao, Padma G. M.</au><au>Majid, Asif</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates</atitle><jtitle>International journal of clinical pharmacy</jtitle><stitle>Int J Clin Pharm</stitle><addtitle>Int J Clin Pharm</addtitle><date>2016-12-01</date><risdate>2016</risdate><volume>38</volume><issue>6</issue><spage>1367</spage><epage>1371</epage><pages>1367-1371</pages><issn>2210-7703</issn><eissn>2210-7711</eissn><abstract>Background Cephalosporins are one of the most commonly used antibiotics in United Arab Emirates (UAE). Few studies have been carried out to evaluate the antibiotic utilization pattern in UAE in spite of the obvious increase in cephalosporins resistance during the past decade. Objective To assess the prescriptions pattern of cephalosporins among physicians at a secondary care hospital in Ras Al Khaimah, UAE. Method This observational prospective study was carried out during October 2013 to April 2014. The data of in patients were documented in the predesigned patient profile form and was analyzed for patient’s, drug’s and drug’s therapy related parameters. Results The 3rd generation cephalosporins constituted 83.6 % of the prescriptions, with ceftriaxone being the most commonly used one (81.1 %). They were mainly prescribed for the treatment of the lower respiratory tract infections (60.2 %). Seven (3.5 %) different ADRs linked to cephalosporin use were observed ranging from oral thrush to clostridium difficile infection. A total of 1039 antimicrobial and nonantimicrobial medications were prescribed concomitantly with cephalosporins. Conclusion The 3rd generation cephalosporins were commonly prescribed by parenteral route. Thus, there is a strong need for rationalizing their use to preserve their efficacy and prevent the development of resistance in the region.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>27817172</pmid><doi>10.1007/s11096-016-0392-4</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 2210-7703
ispartof International journal of clinical pharmacy, 2016-12, Vol.38 (6), p.1367-1371
issn 2210-7703
2210-7711
language eng
recordid cdi_proquest_miscellaneous_1850781561
source Springer Nature
subjects Adolescent
Adult
Aged
Anti-Bacterial Agents
Antibiotics
Cephalosporins
Clostridium difficile
Drug therapy
Drug use
Drug Utilization Review - methods
Female
Hospitals
Humans
Internal Medicine
Male
Medicine
Medicine & Public Health
Middle Aged
Pharmacy
Prospective Studies
Respiratory diseases
Secondary Care - standards
Secondary Care - trends
Secondary Care Centers - standards
Secondary Care Centers - trends
Short Research Report
United Arab Emirates - epidemiology
Young Adult
title Drug utilization review of cephalosporins in a secondary care hospital in United Arab Emirates
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T02%3A55%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Drug%20utilization%20review%20of%20cephalosporins%20in%20a%20secondary%20care%20hospital%20in%20United%20Arab%20Emirates&rft.jtitle=International%20journal%20of%20clinical%20pharmacy&rft.au=Abou-Shaaban,%20Mohammad&rft.date=2016-12-01&rft.volume=38&rft.issue=6&rft.spage=1367&rft.epage=1371&rft.pages=1367-1371&rft.issn=2210-7703&rft.eissn=2210-7711&rft_id=info:doi/10.1007/s11096-016-0392-4&rft_dat=%3Cproquest_cross%3E1850781561%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c405t-8b1b76050f1fa0ba6471a26c4f80fba94316c6a7255b8da1d54440724cd6f2003%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1843255672&rft_id=info:pmid/27817172&rfr_iscdi=true