Long-Term Quality of Life in Adult Survivors of Pediatric Differentiated Thyroid Carcinoma

• Published in: The journal of clinical endocrinology and metabolism 2017-04, Vol.102 (4), p.1218-1226
• Main Authors: Nies, Marloes, Klein Hesselink, Mariëlle S, Huizinga, Gea A, Sulkers, Esther, Brouwers, Adrienne H, Burgerhof, Johannes G M, van Dam, Eveline W. C M, Havekes, Bas, van den Heuvel-Eibrink, Marry M, Corssmit, Eleonora P M, Kremer, Leontien C M, Netea-Maier, Romana T, van der Pal, Heleen J H, Peeters, Robin P, Plukker, John T M, Ronckers, Cécile M, van Santen, Hanneke M, Tissing, Wim J E, Links, Thera P, Bocca, Gianni
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Age; Anxiety; Anxiety - psychology; Depression - psychology; Fatigue; Fatigue - psychology; Female; Follow-Up Studies; Humans; Impairment; Life assessment; Male; Medical treatment; Mental depression; Mental Fatigue - psychology; Middle Aged; Pediatrics; Quality of life; Quality of Life - psychology; Socioeconomics; Survivors - psychology; Thyroid cancer; Thyroid carcinoma; Thyroid Neoplasms - therapy; Young Adult
• ISSN: 0021-972X; 1945-7197
• DOI: 10.1210/jc.2016-2246

Little is known about long-term quality of life (QoL) of survivors of pediatric differentiated thyroid carcinoma. Therefore, this study aimed to evaluate generic health-related QoL (HRQoL), fatigue, anxiety, and depression in these survivors compared with matched controls, and to evaluate thyroid cancer-specific HRQoL in survivors only. Survivors diagnosed between 1970 and 2013 at age ≤18 years, were included. Exclusion criteria were a follow-up