Longitudinal association of antidepressant medication use with metabolic syndrome: Results of a 9-year follow-up of the D.E.S.I.R. cohort study

Highlights • We found an association between antidepressant use and the MetS over the follow-up in men but not in women. • This association was evident for selective serotonin reuptake inhibitors, imipramine type and “other” antidepressants. • People on antidepressants may need to be checked regular...

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Bibliographic Details
Published in:Psychoneuroendocrinology 2016-12, Vol.74, p.34-45
Main Authors: Azevedo Da Silva, Marine, MSc, Balkau, Beverley, PhD, Roussel, Ronan, MD, Tichet, Jean, MD, Fumeron, Frédéric, PhD, Fagherazzi, Guy, PhD, Nabi, Hermann, PhD
Format: Article
Language:English
Subjects:
Adult
Aged
AHA/NHLBI
Antidepressant
Antidepressive Agents - adverse effects
Antidepressive Agents, Tricyclic - adverse effects
Cohort study
Endocrinology & Metabolism
Female
Follow-Up Studies
France - epidemiology
Humans
Longitudinal Studies
Male
Metabolic syndrome
Metabolic Syndrome - chemically induced
Metabolic Syndrome - epidemiology
Middle Aged
NCEP-ATP III
Prospective study
Psychiatry
Serotonin Uptake Inhibitors - adverse effects
Sex Factors
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Summary:Highlights • We found an association between antidepressant use and the MetS over the follow-up in men but not in women. • This association was evident for selective serotonin reuptake inhibitors, imipramine type and “other” antidepressants. • People on antidepressants may need to be checked regularly for the elements of the metabolic syndrome.
ISSN:0306-4530
1873-3360
DOI:10.1016/j.psyneuen.2016.08.020