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Precancerous lesions of the buccal epithelium

Squamous cell carcinomas of the oral cavity and lips consistently have a high incidence (they constitute the fifth most common form of cancer in France) and carry a heavy prognosis, particularly if diagnosed late. According to different studies, between 10 and 80% of such carcinomas occur in a pre-e...

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Bibliographic Details
Published in:Annales de dermatologie et de vénéréologie 2017-02, Vol.144 (2), p.100-108
Main Authors: Renaud-Vilmer, C, Cavelier-Balloy, B
Format: Article
Language:fre
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Summary:Squamous cell carcinomas of the oral cavity and lips consistently have a high incidence (they constitute the fifth most common form of cancer in France) and carry a heavy prognosis, particularly if diagnosed late. According to different studies, between 10 and 80% of such carcinomas occur in a pre-existing or precancerous lesion. The World Health Organisation (WHO) recommends the use of two terms for such lesions: precursor lesions, i.e. histological lesions associated with intraepithelial neoplasia (IEN) and verrucous hyperplasia (VH), frequently resulting clinically in leukoplakia or erythroplakia; "at risk" lesions, which include lichen planus, submucosal oral fibrosis and certain forms of genodermatosis.
ISSN:0151-9638
DOI:10.1016/j.annder.2016.07.017