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Classification of patients with chronic obstructive pulmonary disease according to the Latin American Thoracic Association (ALAT) staging systems and the global initiative for chronic obstructive pulmonary disease (GOLD)
Several classification systems use different criteria when assessing COPD stages. The objective of this study was to compare the prevalence and distribution of COPD stagesusing Global initiative for chronic Obstructive Lung Disease (GOLD) recommendationsand Latin American Thoracic Association (ALAT)...
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Published in: | Archivos de bronconeumología (English ed.) 2017-03, Vol.53 (3), p.98-106 |
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container_title | Archivos de bronconeumología (English ed.) |
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creator | Montes de Oca, Maria López Varela, María Victorina Laucho-Contreras, María Eugenia Casas, Alejandro Schiavi, Eduardo Rey, Alejandra Silva, Alejandra |
description | Several classification systems use different criteria when assessing COPD stages. The objective of this study was to compare the prevalence and distribution of COPD stagesusing Global initiative for chronic Obstructive Lung Disease (GOLD) recommendationsand Latin American Thoracic Association (ALAT) guidelinesin a primary-care population.
Subjects attending routine primary care visits, ≥40 years of age, current or former smokers or exposed to biomass, completed a questionnaire and performed spirometry. COPD was defined as post-bronchodilator FEV
/FVC |
doi_str_mv | 10.1016/j.arbres.2016.08.015 |
format | article |
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Subjects attending routine primary care visits, ≥40 years of age, current or former smokers or exposed to biomass, completed a questionnaire and performed spirometry. COPD was defined as post-bronchodilator FEV
/FVC<0.70 and categorised according to GOLD-2013 criteria and ALAT-2014 guideline. The BODEx index was used to assess the prognostic value of the stratification systems.
A total of 1743 subjects completed the interview, 1540 performed acceptable spirometry. COPD prevalence according GOLD-2013 was 20.1% and had a U-shaped stage distribution (group A: 9.3%, B: 4.3%, C: 2.0%, D: 4.6%). According to ALAT, prevalence was 19.7% with a bell-shaped stage distribution (mild: 2.9%, moderate: 9%, severe: 5.4%, very-severe: 2.7%). Approximately 73% of patients were stratified as moderate (45.4%) or severe (27.3%) by ALAT guidelines, whereas using GOLD-2013 criteria the majority of subjects (approximately 69%) were in group A (46.3%) or group B (22.7%). BODE index score increased as COPD worsened according to ALAT stratification. This is not observed with GOLD2013 criteria (similar values for B and C groups).
Disease stages differ under ALAT and GOLD-2013 criteria. ALAT identified a greater proportion of COPD subjects in the moderate and severe categories compared with GOLD-2013, where the majority were categorised in group A. Future evaluation of the ALAT classification should address its predictive ability in terms of hospitalizations and mortality.</description><identifier>EISSN: 1579-2129</identifier><identifier>DOI: 10.1016/j.arbres.2016.08.015</identifier><identifier>PMID: 27956034</identifier><language>eng ; spa</language><publisher>Spain</publisher><subject>Adult ; Female ; Humans ; Male ; Middle Aged ; Practice Guidelines as Topic ; Pulmonary Disease, Chronic Obstructive - classification ; Pulmonary Disease, Chronic Obstructive - diagnosis ; Severity of Illness Index</subject><ispartof>Archivos de bronconeumología (English ed.), 2017-03, Vol.53 (3), p.98-106</ispartof><rights>Copyright © 2016 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27956034$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Montes de Oca, Maria</creatorcontrib><creatorcontrib>López Varela, María Victorina</creatorcontrib><creatorcontrib>Laucho-Contreras, María Eugenia</creatorcontrib><creatorcontrib>Casas, Alejandro</creatorcontrib><creatorcontrib>Schiavi, Eduardo</creatorcontrib><creatorcontrib>Rey, Alejandra</creatorcontrib><creatorcontrib>Silva, Alejandra</creatorcontrib><creatorcontrib>en nombre del equipo del estudio PUMA</creatorcontrib><title>Classification of patients with chronic obstructive pulmonary disease according to the Latin American Thoracic Association (ALAT) staging systems and the global initiative for chronic obstructive pulmonary disease (GOLD)</title><title>Archivos de bronconeumología (English ed.)</title><addtitle>Arch Bronconeumol</addtitle><description>Several classification systems use different criteria when assessing COPD stages. The objective of this study was to compare the prevalence and distribution of COPD stagesusing Global initiative for chronic Obstructive Lung Disease (GOLD) recommendationsand Latin American Thoracic Association (ALAT) guidelinesin a primary-care population.
Subjects attending routine primary care visits, ≥40 years of age, current or former smokers or exposed to biomass, completed a questionnaire and performed spirometry. COPD was defined as post-bronchodilator FEV
/FVC<0.70 and categorised according to GOLD-2013 criteria and ALAT-2014 guideline. The BODEx index was used to assess the prognostic value of the stratification systems.
A total of 1743 subjects completed the interview, 1540 performed acceptable spirometry. COPD prevalence according GOLD-2013 was 20.1% and had a U-shaped stage distribution (group A: 9.3%, B: 4.3%, C: 2.0%, D: 4.6%). According to ALAT, prevalence was 19.7% with a bell-shaped stage distribution (mild: 2.9%, moderate: 9%, severe: 5.4%, very-severe: 2.7%). Approximately 73% of patients were stratified as moderate (45.4%) or severe (27.3%) by ALAT guidelines, whereas using GOLD-2013 criteria the majority of subjects (approximately 69%) were in group A (46.3%) or group B (22.7%). BODE index score increased as COPD worsened according to ALAT stratification. This is not observed with GOLD2013 criteria (similar values for B and C groups).
Disease stages differ under ALAT and GOLD-2013 criteria. ALAT identified a greater proportion of COPD subjects in the moderate and severe categories compared with GOLD-2013, where the majority were categorised in group A. Future evaluation of the ALAT classification should address its predictive ability in terms of hospitalizations and mortality.</description><subject>Adult</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Practice Guidelines as Topic</subject><subject>Pulmonary Disease, Chronic Obstructive - classification</subject><subject>Pulmonary Disease, Chronic Obstructive - diagnosis</subject><subject>Severity of Illness Index</subject><issn>1579-2129</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNqNkUFu2zAQRYkAQZMmvUERcOksrJCUSEtLwU2TAAK8cdcGSZE2DYlUOVSL3DWHKZ24-6xmBvjz_scMQt8pKSih4uFYyKiigYLlqSB1QSi_QNeUr5olo6y5Ql8BjoQIQSn9gq7YquGClNU1elsPEsBZp2VyweNg8ZQ74xPgvy4dsD7E4J3GQUGKs07uj8HTPIzBy_iKewdGgsFS6xB75_c4BZwOBncZ4nE7mpjJHm8PIUqdMS1A0O7Da9F27fYeQ5L70ya8QjIjYOn7d8R-CEoO2HmXTgvZ14b4yTyLp0334_4WXVo5gPl2rjfo18_H7fp52W2eXtZtt5wYpWlZVjWxjdW1bfJdbFNJyWpGrLalKJVQwtq6UVZT3vNKNVasuDK1ELY0nFS9Km_Q4oM7xfB7NpB2owNthkF6E2bY0ZozIbioWJbenaWzGk2_m6Ibc_Dd_4-U_wAQcZPK</recordid><startdate>201703</startdate><enddate>201703</enddate><creator>Montes de Oca, Maria</creator><creator>López Varela, María Victorina</creator><creator>Laucho-Contreras, María Eugenia</creator><creator>Casas, Alejandro</creator><creator>Schiavi, Eduardo</creator><creator>Rey, Alejandra</creator><creator>Silva, Alejandra</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201703</creationdate><title>Classification of patients with chronic obstructive pulmonary disease according to the Latin American Thoracic Association (ALAT) staging systems and the global initiative for chronic obstructive pulmonary disease (GOLD)</title><author>Montes de Oca, Maria ; López Varela, María Victorina ; Laucho-Contreras, María Eugenia ; Casas, Alejandro ; Schiavi, Eduardo ; Rey, Alejandra ; Silva, Alejandra</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p211t-3480f9fc8f9795f94aa2820fcf363b6b6ff89bfc15d54b9f675be866f3e504db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; spa</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Practice Guidelines as Topic</topic><topic>Pulmonary Disease, Chronic Obstructive - classification</topic><topic>Pulmonary Disease, Chronic Obstructive - diagnosis</topic><topic>Severity of Illness Index</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Montes de Oca, Maria</creatorcontrib><creatorcontrib>López Varela, María Victorina</creatorcontrib><creatorcontrib>Laucho-Contreras, María Eugenia</creatorcontrib><creatorcontrib>Casas, Alejandro</creatorcontrib><creatorcontrib>Schiavi, Eduardo</creatorcontrib><creatorcontrib>Rey, Alejandra</creatorcontrib><creatorcontrib>Silva, Alejandra</creatorcontrib><creatorcontrib>en nombre del equipo del estudio PUMA</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Archivos de bronconeumología (English ed.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Montes de Oca, Maria</au><au>López Varela, María Victorina</au><au>Laucho-Contreras, María Eugenia</au><au>Casas, Alejandro</au><au>Schiavi, Eduardo</au><au>Rey, Alejandra</au><au>Silva, Alejandra</au><aucorp>en nombre del equipo del estudio PUMA</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Classification of patients with chronic obstructive pulmonary disease according to the Latin American Thoracic Association (ALAT) staging systems and the global initiative for chronic obstructive pulmonary disease (GOLD)</atitle><jtitle>Archivos de bronconeumología (English ed.)</jtitle><addtitle>Arch Bronconeumol</addtitle><date>2017-03</date><risdate>2017</risdate><volume>53</volume><issue>3</issue><spage>98</spage><epage>106</epage><pages>98-106</pages><eissn>1579-2129</eissn><abstract>Several classification systems use different criteria when assessing COPD stages. The objective of this study was to compare the prevalence and distribution of COPD stagesusing Global initiative for chronic Obstructive Lung Disease (GOLD) recommendationsand Latin American Thoracic Association (ALAT) guidelinesin a primary-care population.
Subjects attending routine primary care visits, ≥40 years of age, current or former smokers or exposed to biomass, completed a questionnaire and performed spirometry. COPD was defined as post-bronchodilator FEV
/FVC<0.70 and categorised according to GOLD-2013 criteria and ALAT-2014 guideline. The BODEx index was used to assess the prognostic value of the stratification systems.
A total of 1743 subjects completed the interview, 1540 performed acceptable spirometry. COPD prevalence according GOLD-2013 was 20.1% and had a U-shaped stage distribution (group A: 9.3%, B: 4.3%, C: 2.0%, D: 4.6%). According to ALAT, prevalence was 19.7% with a bell-shaped stage distribution (mild: 2.9%, moderate: 9%, severe: 5.4%, very-severe: 2.7%). Approximately 73% of patients were stratified as moderate (45.4%) or severe (27.3%) by ALAT guidelines, whereas using GOLD-2013 criteria the majority of subjects (approximately 69%) were in group A (46.3%) or group B (22.7%). BODE index score increased as COPD worsened according to ALAT stratification. This is not observed with GOLD2013 criteria (similar values for B and C groups).
Disease stages differ under ALAT and GOLD-2013 criteria. ALAT identified a greater proportion of COPD subjects in the moderate and severe categories compared with GOLD-2013, where the majority were categorised in group A. Future evaluation of the ALAT classification should address its predictive ability in terms of hospitalizations and mortality.</abstract><cop>Spain</cop><pmid>27956034</pmid><doi>10.1016/j.arbres.2016.08.015</doi><tpages>9</tpages></addata></record> |
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subjects | Adult Female Humans Male Middle Aged Practice Guidelines as Topic Pulmonary Disease, Chronic Obstructive - classification Pulmonary Disease, Chronic Obstructive - diagnosis Severity of Illness Index |
title | Classification of patients with chronic obstructive pulmonary disease according to the Latin American Thoracic Association (ALAT) staging systems and the global initiative for chronic obstructive pulmonary disease (GOLD) |
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