Photoredox-Induced Functionalization of Alkenes for the Synthesis of Substituted Imidazolines and Oxazolidines

A one-pot, three-component cascade reaction combining photoredox catalyzed radical addition and formal [3 + 2] annulation was developed. With this approach, highly concise syntheses of imidazoline and oxazolidine derivatives have been achieved. The advantages of this transformation are good to excel...

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Bibliographic Details
Published in:Journal of organic chemistry 2017-01, Vol.82 (1), p.243-249
Main Authors: Chen, Jian-Qiang, Yu, Wan-Lei, Wei, Yun-Long, Li, Teng-Hui, Xu, Peng-Fei
Format: Article
Language:English
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Summary:A one-pot, three-component cascade reaction combining photoredox catalyzed radical addition and formal [3 + 2] annulation was developed. With this approach, highly concise syntheses of imidazoline and oxazolidine derivatives have been achieved. The advantages of this transformation are good to excellent yields, mild reaction conditions, operational simplicity, and easy accessibility of raw materials.
ISSN:0022-3263
1520-6904
DOI:10.1021/acs.joc.6b02377