Early Detection of Bone Metastasis in Small Cell Neuroendocrine Carcinoma of the Cervix by 68Ga-DOTATATE PET/CT Imaging

ABSTRACTThe neuroendocrine small cell carcinoma of the cervix is a rare malignancy that has a poor prognosis due to early lymphatic and hematogenous spread. We herein report a case of a 27- year-old woman who was referred for initial staging of a neuroendocrine small cell carcinoma with previous unr...

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Bibliographic Details
Published in:Clinical nuclear medicine 2017-03, Vol.42 (3), p.216-217
Main Authors: Damian, Andres, Lago, Graciela, Rossi, Susana, Alonso, Omar, Engler, Henry
Format: Article
Language:English
Subjects:
Adult
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - secondary
Carcinoma, Neuroendocrine - diagnostic imaging
Carcinoma, Neuroendocrine - pathology
Carcinoma, Small Cell - diagnostic imaging
Carcinoma, Small Cell - pathology
Female
Humans
Organometallic Compounds
Positron Emission Tomography Computed Tomography
Radiopharmaceuticals
Uterine Cervical Neoplasms - diagnostic imaging
Uterine Cervical Neoplasms - pathology
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Summary:ABSTRACTThe neuroendocrine small cell carcinoma of the cervix is a rare malignancy that has a poor prognosis due to early lymphatic and hematogenous spread. We herein report a case of a 27- year-old woman who was referred for initial staging of a neuroendocrine small cell carcinoma with previous unremarkable structural imaging. Ga-DOTATATE PET/CT revealed focal uptake at the primary tumor and in a solitary pelvic bone lesion suggestive of metastases that was further confirmed by CT-guided biopsy. Somatostatin receptor PET/CT may be a useful image modality for early detection of metastases to guide treatment in these patients.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000001498