Reliability of reporting the presence of transformation zone material in Papanicolaou smears using an automated screening system

Objective This study was conducted to evaluate the reliability of using an interactive automated screening system (IAS) to determine the presence of endocervical and/or metaplastic cells (transformation zone material; TZM) in liquid‐based cytology (LBC) Papanicolaou (Pap) smear slides. Materials and...

Full description

Saved in:
Bibliographic Details
Published in:Cytopathology (Oxford) 2017-08, Vol.28 (4), p.280-283
Main Authors: Erbarut Seven, I., Mollamemisoglu, H., Eren, F.
Format: Article
Language:English
Subjects:
Adult
Aged
automated screening system
Automation
Cellular biology
Cervix Uteri - pathology
Cytology
endocervical cells
Female
Humans
liquid based
Mass Screening
Middle Aged
Pap smear
Papanicolaou smear
Papanicolaou Test - methods
Reproducibility of Results
Research Report
transformation zone material
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective This study was conducted to evaluate the reliability of using an interactive automated screening system (IAS) to determine the presence of endocervical and/or metaplastic cells (transformation zone material; TZM) in liquid‐based cytology (LBC) Papanicolaou (Pap) smear slides. Materials and methods A series of LBC Pap smears was manually screened to determine the presence or absence of TZM. The results were compared to those obtained through IAS. Results ThinPrep® Imaging System (Imager)‐assisted screening indicated that 22.4% of the slides did not contain TZM in cases in which previous manual screening revealed that 100% of the slides did contain TZM. Conclusion The reliability of determining TZM through IAS is limited. Manual screening of the slides appears to be necessary to report the presence of TZM accurately. Automated screening systems are now widely used to facilitate assessment of liquid based cytology smears. In this study, the efficacy of detection of transformation zone material using an interactive system was assessed.
ISSN:0956-5507
1365-2303
DOI:10.1111/cyt.12411