Nasopharyngeal Pneumococcal Carriage During Childhood Community-Acquired Alveolar Pneumonia: Relationship Between Specific Serotypes and Coinfecting Viruses

Background. Respiratory viruses and Streptococcus pneumoniae are known to be copathogens in childhood pneumonia. However, it is unclear whether all pneumococcal serotypes are equally prone to such interaction. We attempted to determine association between carried pneumococcal serotypes and respirato...

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Bibliographic Details
Published in:The Journal of infectious diseases 2017-04, Vol.215 (7), p.1111-1116
Main Authors: Greenberg, David, Givon-Lavi, Noga, Faingelernt, Yaniv, Ben-Shimol, Shalom, Avni, Yonat Shemer, Bar-Ziv, Jacob, Dagan, Ron
Format: Article
Language:English
Subjects:
BACTERIA
Carrier State - epidemiology
Child, Preschool
Coinfection - microbiology
Coinfection - virology
Community-Acquired Infections - epidemiology
Community-Acquired Infections - microbiology
Community-Acquired Infections - virology
Female
Humans
Infant
Infant, Newborn
Israel
Male
Nasopharynx - microbiology
Nasopharynx - virology
Pneumonia, Pneumococcal - epidemiology
Pneumonia, Pneumococcal - virology
Respiratory Syncytial Virus, Human
Serogroup
Streptococcus pneumoniae - classification
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Summary:Background. Respiratory viruses and Streptococcus pneumoniae are known to be copathogens in childhood pneumonia. However, it is unclear whether all pneumococcal serotypes are equally prone to such interaction. We attempted to determine association between carried pneumococcal serotypes and respiratory viruses during childhood community-acquired alveolar pneumonia (CAAP). Methods. The study was conducted during respiratory syncytial virus (RSV) seasons, before pneumococcal vaccine introduction. Children aged
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/jiw613