Early diagnosis of Ehrlichia ewingii infection in a lung transplant recipient by peripheral blood smear

Ehrlichiosis in lung transplant (LT) recipients is associated with severe outcomes. Ehrlichia ewingii is a less frequent cause of symptomatic ehrlichiosis, characterized by cytoplasmic inclusions (morulae) within circulating neutrophils. We report a case of E. ewingii infection in an LT recipient di...

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Bibliographic Details
Published in:Transplant infectious disease 2017-04, Vol.19 (2), p.n/a
Main Authors: Regunath, Hariharan, Rojas‐Moreno, Christian, Olano, Juan P., Hammer, Richard D., Salzer, William
Format: Article
Language:English
Subjects:
Aged
Animals
Anti-Bacterial Agents - therapeutic use
blood smear
Cytodiagnosis - methods
Disease Transmission, Infectious
DNA, Bacterial - isolation & purification
doxycycline
Doxycycline - therapeutic use
Early Diagnosis
Ehrlichia - isolation & purification
Ehrlichia ewingii
Ehrlichiosis - blood
Ehrlichiosis - diagnosis
Ehrlichiosis - drug therapy
Ehrlichiosis - microbiology
Female
fever
Fever - blood
Fever - diagnosis
Fever - drug therapy
Fever - microbiology
Graft Rejection - drug therapy
Humans
Immunosuppression - adverse effects
Immunosuppression - methods
Immunosuppressive Agents - adverse effects
Immunosuppressive Agents - therapeutic use
Ixodidae - microbiology
Leukopenia - blood
lung transplant
Lung Transplantation - adverse effects
Mycophenolic Acid - adverse effects
Mycophenolic Acid - therapeutic use
Neutrophils - microbiology
Polymerase Chain Reaction
Prednisone - adverse effects
Prednisone - therapeutic use
Tacrolimus - adverse effects
Tacrolimus - therapeutic use
Thoracentesis
Thrombocytopenia - blood
Tomography, X-Ray Computed
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Description
Summary:Ehrlichiosis in lung transplant (LT) recipients is associated with severe outcomes. Ehrlichia ewingii is a less frequent cause of symptomatic ehrlichiosis, characterized by cytoplasmic inclusions (morulae) within circulating neutrophils. We report a case of E. ewingii infection in an LT recipient diagnosed promptly by blood smear exam and confirmed with molecular studies.
ISSN:1398-2273
1399-3062
DOI:10.1111/tid.12652