The response of skeletal muscle to alcohol abuse: Gender differences

A gender analysis has been carried out to analyze changes in intracellular signaling pathways that lead to the development of chronic alcoholic myopathy. It is known that acute or chronic alcohol intoxication can result in alcohol-induced lesions in skeletal muscles. Chronic alcoholic myopathy occur...

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Bibliographic Details
Published in:Biophysics (Oxford) 2016-09, Vol.61 (5), p.793-796
Main Authors: Shenkman, B. S., Zinovyeva, O. E., Belova, S. P., Samkhaeva, N. D., Shcheglova, N. S., Mirzoev, T. M., Vilchinskaya, N. A., Altaeva, E. G., Turtikova, O. V., Nemirovskaya, T. L.
Format: Article
Language:English
Subjects:
Alcohol use
Analysis
Biological and Medical Physics
Biophysics
Complex Systems Biophysics
Gender differences
Musculoskeletal system
Physics
Physics and Astronomy
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Summary:A gender analysis has been carried out to analyze changes in intracellular signaling pathways that lead to the development of chronic alcoholic myopathy. It is known that acute or chronic alcohol intoxication can result in alcohol-induced lesions in skeletal muscles. Chronic alcoholic myopathy occurs much more frequently and can develop either independently or in combination with other forms of alcoholic disease (liver and heart lesions, malabsorption syndrome, or alcohol polyneuropathy). This disease is manifested by atrophy of skeletal muscles and a performance decrement. Most of the studies on the pathogenesis of chronic alcoholic myopathy have been carried out on male patients. Studies on alcoholic myopathy-induced muscle damage in females have not been previously reported.
ISSN:0006-3509
1555-6654
DOI:10.1134/S0006350916050262