Usefulness of the renal resistive index to predict an increase in urinary albumin excretion in patients with essential hypertension

Microalbuminuria is a risk factor for cardiovascular events and death in hypertensive patients. Patients who are expected to increase albuminuria need strict blood pressure control. In the present study, we assessed the association between the renal resistive index (RI) and future increases in album...

Full description

Saved in:
Bibliographic Details
Published in:Journal of human hypertension 2017-01, Vol.31 (1), p.66-69
Main Authors: Miyoshi, K, Okura, T, Tanino, A, Kukida, M, Nagao, T, Higaki, J
Format: Article
Language:English
Subjects:
631/443/1338/243
631/443/1338/2729
Aged
Albumin
Albuminuria
Albuminuria - diagnostic imaging
Analysis
Blood Flow Velocity
Complications and side effects
Development and progression
Diagnosis
Epidemiology
Essential hypertension
Essential Hypertension - diagnostic imaging
Essential Hypertension - urine
Female
Health Administration
Humans
Hypertension
Male
Medicine
Medicine & Public Health
Middle Aged
original-article
Physiological aspects
Public Health
Risk factors
Statistics
Ultrasonography, Doppler, Pulsed
Urinalysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Microalbuminuria is a risk factor for cardiovascular events and death in hypertensive patients. Patients who are expected to increase albuminuria need strict blood pressure control. In the present study, we assessed the association between the renal resistive index (RI) and future increases in albuminuria in patients with essential hypertension. Sixty-six patients with essential hypertension were included in the study. Univariate and multivariate logistic regression analyses were used to identify the factors, including renal RI, that were significant independent determinants of increased in urinary albumin excretion (UAE), defined as an increase of >50% in the urinary albumin-to-creatinine ratio over 2 years. Receiver operator characteristics curve analysis was used to select the optimal cut-off point that predicted an increase in UAE. RI was the only significant variable that predicted the increase in UAE, with the optimal cut-off value of renal RI that predicted this increase being 0.71 (sensitivity 52.4% and specificity 84.4%). Renal RI is associated with the future increase in albuminuria in patients with essential hypertension.
ISSN:0950-9240
1476-5527
DOI:10.1038/jhh.2016.38