Hydrogel films and microcapsules based on soy protein isolate combined with alginate

ABSTRACT Alginate hydrogels are combined with soy protein isolate (SPI), a plant derived protein with low immunogenicity, appropriate biodegradability and low cost, to produce biocompatible films, and microcapsules. The cell–material interaction is assessed through the use of mouse embryotic fibrobl...

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Bibliographic Details
Published in:Journal of applied polymer science 2017-01, Vol.134 (4), p.np-n/a
Main Authors: Tansaz, Samira, Durmann, Ann‐Katrin, Detsch, Rainer, Boccaccini, Aldo R.
Format: Article
Language:English
Subjects:
alginate
Alginates
Biomaterials
biomedical applications
Biomedical materials
Degradation
Fibroblasts
Hydrogels
Materials science
Polymers
Proteins
soy protein isolate
Surgical implants
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Summary:ABSTRACT Alginate hydrogels are combined with soy protein isolate (SPI), a plant derived protein with low immunogenicity, appropriate biodegradability and low cost, to produce biocompatible films, and microcapsules. The cell–material interaction is assessed through the use of mouse embryotic fibroblast cells (MEF cells) on films, and the results illustrate that the alginate/SPI hydrogel films support cell attachment, spreading, and proliferation. Cell biology results combined with degradation studies suggest that such hydrogels are promising biomaterials for soft tissue regeneration or as wound dressing materials. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44358.
ISSN:0021-8995
1097-4628
DOI:10.1002/app.44358