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Development of a MPPC-based prototype gantry for future MRI-PET scanners
We have developed a high spatial resolution, compact Positron Emission Tomography (PET) module designed for small animals and intended for use in magnetic resonance imaging (MRI) systems. This module consists of large-area, 4 x 4 ch MPPC arrays (S11830-3344MF; Hamamatsu Photonics K.K.) optically cou...
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Published in: | Journal of instrumentation 2014-12, Vol.9 (12), p.C12052-C12052 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | We have developed a high spatial resolution, compact Positron Emission Tomography (PET) module designed for small animals and intended for use in magnetic resonance imaging (MRI) systems. This module consists of large-area, 4 x 4 ch MPPC arrays (S11830-3344MF; Hamamatsu Photonics K.K.) optically coupled with Ce-doped (Lu,Y) sub(2)(SiO sub(4))O (Ce:LYSO) scintillators fabricated into 16 x 16 matrices of 0.5 x 0.5 mm super(2) pixels. We set the temperature sensor (LM73CIMK-0; National Semiconductor Corp.) at the rear of the MPPC acceptance surface, and apply optimum voltage to maintain the gain. The eight MPPC-based PET modules and coincidence circuits were assembled into a gantry arranged in a ring 90 mm in diameter to form the MPPC-based PET system. We have developed two types PET gantry: one made of non-magnetic metal and the other made of acrylonitrile butadiene styrene (ABS) resins. The PET gantry was positioned around the RF coil of the 4.7 T MRI system. We took an image of a point } super(22)Na source under fast spin echo (FSE) and gradient echo (GE), in order to measure the interference between the MPPC-based PET and MRI. The spatial resolution of PET imaging in a transaxial plane of about 1 mm (FWHM) was achieved in all cases. Operating with PET made of ABS has no effect on MR images, while operating with PET made of non-magnetic metal has a significant detrimental effect on MR images. This paper describes our quantitative evaluations of PET images and MR images, and presents a more advanced version of the gantry for future MRI/DOI-PET systems. |
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ISSN: | 1748-0221 1748-0221 |
DOI: | 10.1088/1748-0221/9/12/C12052 |