A new brain stimulation method： Noninvasive transcranial magneto–acoustical stimulation

We investigate transcranial magneto–acoustical stimulation（TMAS） for noninvasive brain neuromodulation in vivo.TMAS as a novel technique uses an ultrasound wave to induce an electric current in the brain tissue in the static magnetic field. It has the advantage of high spatial resolution and penetra...

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Bibliographic Details
Published in:Chinese physics B 2016-08, Vol.25 (8), p.222-227
Main Author: 袁毅 陈玉东 李小俚
Format: Article
Language:English
Subjects:
Brain
Diagnostic systems
In vivo methods and tests
Magnetic fields
Neurons
Rats
Stimulation
Ultrasound
侵入性
动作电位
神经元
神经调节
空间分辨率
穿透深度
经颅磁刺激
脑电
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Summary:We investigate transcranial magneto–acoustical stimulation（TMAS） for noninvasive brain neuromodulation in vivo.TMAS as a novel technique uses an ultrasound wave to induce an electric current in the brain tissue in the static magnetic field. It has the advantage of high spatial resolution and penetration depth. The mechanism of TMAS onto a neuron is analyzed by combining the TMAS principle and Hodgkin–Huxley neuron model. The anesthetized rats are stimulated by TMAS, resulting in the local field potentials which are recorded and analyzed. The simulation results show that TMAS can induce neuronal action potential. The experimental results indicate that TMAS can not only increase the amplitude of local field potentials but also enhance the effect of focused ultrasound stimulation on the neuromodulation. In summary, TMAS can accomplish brain neuromodulation, suggesting a potentially powerful noninvasive stimulation method to interfere with brain rhythms for diagnostic and therapeutic purposes.
ISSN:1674-1056
2058-3834
1741-4199
DOI:10.1088/1674-1056/25/8/084301