Gallstone disease is associated with arterial stiffness progression

Gallstones have been linked to dyslipidemia, metabolic syndrome and cardiovascular disease. Arterial stiffness is an indicator of subclinical atherosclerosis. The aim of this study was to prospectively examine the relationship between gallstone disease and arterial stiffness progression in 347 men a...

Full description

Saved in:
Bibliographic Details
Published in:Hypertension research 2017-01, Vol.40 (1), p.31-34
Main Authors: Yu, Kai-Jing, Zhang, Ji-Rong, Li, Ying, Huang, Xiaoyi, Liu, Tiemin, Li, Chuanfu, Wang, Rui-Tao
Format: Article
Language:English
Subjects:
Adult
Ankle Brachial Index
Cardiovascular Diseases - physiopathology
Disease Progression
Female
Gallstones - physiopathology
Humans
Male
Middle Aged
Prospective Studies
Pulse Wave Analysis
Risk Factors
Vascular Stiffness - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Gallstones have been linked to dyslipidemia, metabolic syndrome and cardiovascular disease. Arterial stiffness is an indicator of subclinical atherosclerosis. The aim of this study was to prospectively examine the relationship between gallstone disease and arterial stiffness progression in 347 men and 454 women. These subjects were followed for 7 years. Arterial stiffness progression was measured based on increases in brachial-ankle pulse wave velocity. Changes in brachial-ankle pulse wave velocity during the study period were significantly greater in patients with gallstones than in subjects without gallstones. After adjusting for multiple risk factors, gallstone disease was found to be a significant and independent predictor of brachial-ankle pulse wave velocity progression (β=0.189; P
ISSN:0916-9636
1348-4214
DOI:10.1038/hr.2016.109