Repeat resection for recurrent pulmonary metastasis of colorectal cancer

• Published in: Langenbeck's archives of surgery 2017-02, Vol.402 (1), p.77-85
• Main Authors: Sponholz, Stefan, Schirren, Moritz, Baldes, Natalie, Oguzhan, Selma, Schirren, Joachim
• Format: Article
• Language: English
• Subjects: Abdominal Surgery; Cardiac Surgery; Colorectal Neoplasms - pathology; Female; General Surgery; Humans; Lung Neoplasms - mortality; Lung Neoplasms - secondary; Lung Neoplasms - surgery; Male; Medicine; Medicine & Public Health; Metastasectomy; Middle Aged; Neoplasm Recurrence, Local - diagnosis; Neoplasm Recurrence, Local - epidemiology; Neoplasm Recurrence, Local - surgery; Original Article; Pneumonectomy; Prevalence; Reoperation; Retrospective Studies; Risk Factors; Survival Rate; Thoracic Surgery; Traumatic Surgery; Vascular Surgery
• ISSN: 1435-2443; 1435-2451
• DOI: 10.1007/s00423-016-1547-4

Purpose Resection of recurrent lung metastases from colorectal cancer is not completely investigated. We analyzed overall survival and prognosticators after metastasectomy. Methods We retrospectively reviewed our database of 238 patients with lung metastases of colorectal cancer, undergoing metastasectomy with systematic lymph node dissection from 1999 to 2014. Lymph node metastases were found in 55 patients, and liver metastases were found in 79 patients. Results The 5- and 10-year survival rates for all patients were 48 and 32%. Of the 238 patients included in the study, 101 developed recurrent lung metastases (42.4%). Recurrence had no impact on survival ( p  = 0.474). The 5- and 10-year survival rates from the beginning of recurrence for all patients with recurrence were 40 and 25%. Overall, 52 patients had been reoperated for recurrent lung metastases. 5-year survival for reoperated patients was 75% and significantly prolonged compared with nonreoperated patients ( p