Genetic variants associated with skin aging in the Chinese Han population

Highlights • This is the first report of a candidate gene study conducted for skin aging signs in Han Chinese. • Our results showed genetic risk factors for skin aging signs (pigmentation, wrinkles or laxity) in Han Chinese, and that these are further modified by anatomical site. • Different genetic...

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Bibliographic Details
Published in:Journal of dermatological science 2017-04, Vol.86 (1), p.21-29
Main Authors: Gao, Wenshan, Tan, Jingze, Hüls, Anke, Ding, Anan, Liu, Yu, Matsui, Mary S, Vierkötter, Andrea, Krutmann, Jean, Schikowski, Tamara, Jin, Li, Wang, Sijia
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Asian Continental Ancestry Group - genetics
Candidate genes
Candidate SNPs
Chinese Han population
Dermatology
Female
Genetic Association Studies
Genetic Variation
Genotype
Humans
Middle Aged
Polymorphism, Single Nucleotide
Risk Factors
Skin aging
Skin Aging - genetics
Surveys and Questionnaires
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Summary:Highlights • This is the first report of a candidate gene study conducted for skin aging signs in Han Chinese. • Our results showed genetic risk factors for skin aging signs (pigmentation, wrinkles or laxity) in Han Chinese, and that these are further modified by anatomical site. • Different genetic variants could be responsible for distinct skin aging signs characteristic of Caucasian compared with an East Asian ethnic group.
ISSN:0923-1811
1873-569X
DOI:10.1016/j.jdermsci.2016.12.017