Concentrations of organophosphorus, polybromobenzene, and polybrominated diphenyl ether flame retardants in human serum, and relationships between concentrations and donor ages

Organophosphorus flame retardants, polybromobenzenes, and polybrominated diphenyl ethers (PBDEs) were determined in pooled human serum samples collected in an area in which these chemicals are produced in North China. Tri (2-chloroethyl) phosphate (TCEP) was found at a higher concentration than the...

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Bibliographic Details
Published in:Chemosphere (Oxford) 2017-03, Vol.171, p.654-660
Main Authors: Li, Peng, Jin, Jun, Wang, Ying, Hu, Jicheng, Xu, Meng, Sun, Yiming, Ma, Yulong
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aged, 80 and over
Benzene Derivatives - blood
China
Environmental Monitoring
Environmental Pollutants - blood
Flame Retardants - analysis
Halogenated Diphenyl Ethers - blood
Humans
Middle Aged
Organophosphorus
Organophosphorus Compounds - blood
Polybrominated diphenyl ethers
Polybromobenzenes
Pooled human serum
Trends
Young Adult
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Summary:Organophosphorus flame retardants, polybromobenzenes, and polybrominated diphenyl ethers (PBDEs) were determined in pooled human serum samples collected in an area in which these chemicals are produced in North China. Tri (2-chloroethyl) phosphate (TCEP) was found at a higher concentration than the other chemicals, and the mean TCEP concentration was 480.4 ng/g lipid. This is the first time TCEP has been detected in human serum from China. The PBDE concentration in serum was found to have decreased between 2007 and 2013. BDE-209 remained the dominant PBDE congener, and its mean concentration was 91.3 ng/g lipid in this study. The polybromobenzene concentrations were relatively low, but pentabromobenzene and pentabromotoluene were found in very many of the samples. The highest TCEP, tris(2-butoxyethyl)phosphate, pentabromobenzene, and pentabromotoluene concentrations were found in samples from young people (
ISSN:0045-6535
1879-1298
DOI:10.1016/j.chemosphere.2016.12.126