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Relationship between serum selenium, sociodemographic variables, other trace elements and lipid profile in an adult Spanish population

Several studies have shown an inverse relationship between selenium status and cardiovascular health, although epidemiologic evidence yielded by the randomized trials did not find a beneficial effect of selenium administration. The aim of this study was to analyze the association between serum selen...

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Published in:Journal of trace elements in medicine and biology 2017-09, Vol.43, p.93-105
Main Authors: González-Estecha, Montserrat, Palazón-Bru, Irene, Bodas-Pinedo, Andrés, Trasobares, Elena, Palazón-Bru, Antonio, Fuentes, Manuel, Cuadrado-Cenzual, M. Ángeles, Calvo-Manuel, Elpidio
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Language:English
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Summary:Several studies have shown an inverse relationship between selenium status and cardiovascular health, although epidemiologic evidence yielded by the randomized trials did not find a beneficial effect of selenium administration. The aim of this study was to analyze the association between serum selenium levels and lipid profile adjusted by age, sex and other associated factors among a general adult population in Spain. We recruited 372 hospital employee volunteers (60 men and 312 women) with a mean age of 47 (SD: 10.9), whom were given a standardized questionnaire. Serum selenium concentration was measured by electrothermal atomization atomic absorption spectrometry. Serum copper and zinc concentrations were measured using flame atomic absorption spectrometry. The mean of serum selenium was 79.5μg/L (SD: 11.7) with no sex-dependent differences. In the multivariate linear regression analysis, the associated factors with the mean levels of selenium were: age (β=0.223; CI 95%: 0.101–0.345), p
ISSN:0946-672X
1878-3252
DOI:10.1016/j.jtemb.2016.12.002