Control of mRNA stability and translation during Drosophila development

Translational control of mRNAs regulates the spatio- temporal production of the proteins they encode. Further refinement of mRNA and protein distribution patterns is brought about by regulation of transcript stability. Genetic and molecular analyses in Drosophila can provide unparalleled insight int...

Full description

Saved in:
Bibliographic Details
Published in:Seminars in cell & developmental biology 1997-12, Vol.8 (6), p.541-549
Main Authors: Cooperstock, RL, Lipshitz, HD
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Translational control of mRNAs regulates the spatio- temporal production of the proteins they encode. Further refinement of mRNA and protein distribution patterns is brought about by regulation of transcript stability. Genetic and molecular analyses in Drosophila can provide unparalleled insight into the developmental functions of the modulation of mRNA translation and stability. These mechanisms play a key role in regulating the production of cell fate determinants, cell cycle regulators and molecular chaperones.Copyright 1997 Academic Press
ISSN:1084-9521
1096-3634
DOI:10.1006/scdb.1997.0179