Polysaccharide Sequencing

The biological significance of glycostructures stimulates the analysis of this class of compounds. To better understand the interaction of structurally diverse heparin‐like structures with proteins, an efficient sequence analysis is necessary. A new approach based on the combination of enzymatic deg...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2000-04, Vol.39 (7), p.1222-1224
Main Author: Mischnick, Petra
Format: Article
Language:English
Subjects:
carbohydrates
mass spectrometry
polysaccharides
sequence analysis
structure elucidation
Online Access:Get full text
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Summary:The biological significance of glycostructures stimulates the analysis of this class of compounds. To better understand the interaction of structurally diverse heparin‐like structures with proteins, an efficient sequence analysis is necessary. A new approach based on the combination of enzymatic degradation, capillary electrophoresis, and MALDI mass spectrometry is described.
ISSN:1433-7851
1521-3773
DOI:10.1002/(SICI)1521-3773(20000403)39:7<1222::AID-ANIE1222>3.0.CO;2-8