A Catalyst for Efficient and Highly Enantioselective Hydrogenation of Aromatic, Heteroaromatic, and α,β-Unsaturated Ketones

PhanePhos−ruthenium−diamine complexes catalyze the asymmetric hydrogenation of a wide range of aromatic, heteroaromatic, and α,β-unsaturated ketones with high activity and excellent enantioselectivity.

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Bibliographic Details
Published in:Organic letters 2000-12, Vol.2 (26), p.4173-4176
Main Authors: Burk, Mark J, Hems, William, Herzberg, Daniela, Malan, Christophe, Zanotti-Gerosa, Antonio
Format: Article
Language:English
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Description
Summary:PhanePhos−ruthenium−diamine complexes catalyze the asymmetric hydrogenation of a wide range of aromatic, heteroaromatic, and α,β-unsaturated ketones with high activity and excellent enantioselectivity.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol000309n